Free-radical-scavenging activity and antioxidant effect of ascophyllan from marine brown algae Padina tetrastromatica

S. Mohsin, R. Mahadevan, G. Muraleedhara Kurup
{"title":"Free-radical-scavenging activity and antioxidant effect of ascophyllan from marine brown algae Padina tetrastromatica","authors":"S. Mohsin,&nbsp;R. Mahadevan,&nbsp;G. Muraleedhara Kurup","doi":"10.1016/j.bionut.2013.08.006","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>Brown seaweeds are rich in sulfated polysaccharides that could potentially be exploited as functional ingredients for </span>human health<span>. Over the years, sulfated polysaccharides with potential pharmacological, nutraceutical<span><span> and functional food<span> properties have been isolated from brown seaweeds. This study was designed to characterise and evaluate the antioxidant activity of a sulfated </span></span>polysaccharide ascophyllan isolated from marine brown algae </span></span></span><em>Padina tetrastromatica</em><span>. Four polysaccharide fractions were purified from crude ascophyllan. Antioxidant activities of the polysaccharide fractions were evaluated by various in vitro assay systems, including 2,2-diphenyl-1-picrylhydrazyl (DPPH), superoxide anion, hydroxyl radical-scavenging activity, lipid peroxidation and reducing power assay. The results showed that the ascophyllan fraction </span><em>AF3</em> showed stronger free-radical-scavenging abilities and had good antioxidant effect. Available data obtained by in vitro models suggest that there is a correlation between the sulfate content and antioxidant activity.</p></div>","PeriodicalId":100182,"journal":{"name":"Biomedicine & Preventive Nutrition","volume":"4 1","pages":"Pages 75-79"},"PeriodicalIF":0.0000,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bionut.2013.08.006","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedicine & Preventive Nutrition","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2210523913000524","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18

Abstract

Brown seaweeds are rich in sulfated polysaccharides that could potentially be exploited as functional ingredients for human health. Over the years, sulfated polysaccharides with potential pharmacological, nutraceutical and functional food properties have been isolated from brown seaweeds. This study was designed to characterise and evaluate the antioxidant activity of a sulfated polysaccharide ascophyllan isolated from marine brown algae Padina tetrastromatica. Four polysaccharide fractions were purified from crude ascophyllan. Antioxidant activities of the polysaccharide fractions were evaluated by various in vitro assay systems, including 2,2-diphenyl-1-picrylhydrazyl (DPPH), superoxide anion, hydroxyl radical-scavenging activity, lipid peroxidation and reducing power assay. The results showed that the ascophyllan fraction AF3 showed stronger free-radical-scavenging abilities and had good antioxidant effect. Available data obtained by in vitro models suggest that there is a correlation between the sulfate content and antioxidant activity.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
海洋褐藻叶青素的自由基清除活性及抗氧化作用
褐海藻富含硫酸多糖,可作为人体健康的功能性成分加以开发利用。多年来,从褐海藻中分离出具有潜在药理、营养和功能性食品特性的硫酸酸化多糖。本研究旨在表征和评价从海洋褐藻中分离的硫酸酸化葡萄树酚多糖的抗氧化活性。从粗葡萄树酚中纯化了4个多糖组分。通过2,2-二苯基-1-苦味酰肼(DPPH)、超氧阴离子、羟基自由基清除活性、脂质过氧化和还原能力等多种体外测定系统评价多糖组分的抗氧化活性。结果表明,葡萄叶青素部分AF3具有较强的自由基清除能力和良好的抗氧化作用。通过体外模型获得的现有数据表明,硫酸盐含量与抗氧化活性之间存在相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Antioxidative potential of chrysin, a flavone in streptozotocin–nicotinamide-induced diabetic rats Antidiabetic therapeutics from natural source: A systematic review Insignificant viability of the granules of probiotic and prebiotic with skimmed milk powder Protective role of Solanum trilobatum (Solanaeace) against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice Molecular docking, isolation and biological evaluation of Rhizophora mucronata flavonoids as anti-nociceptive agents
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1