Lokivetmab – a new option for the treatment and control of canine atopic dermatitis – review

Mariana B. Mascarenhas, Cristiane Bazaga Botelho
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Abstract

Monoclonal antibodies have been studied in human medicine for a while. They target specific receptors and cytokines, and are highly specific and effective in blocking their target molecule. Lokivetmab is a monoclonal caninised anti-IL-31 antibody that was recently approved for the treatment of atopic dermatitis in dogs. Currently, no other therapeutic monoclonal antibody is used in veterinary medicine. The goal of this review of literature is to updte clinicians on this new biological option for treatment of canine atopic dermatitis.
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Lokivetmab -治疗和控制犬特应性皮炎的新选择综述
单克隆抗体在人类医学上的研究已有一段时间。它们针对特定的受体和细胞因子,并且具有高度特异性和有效的阻断其靶分子。Lokivetmab是一种单克隆犬抗il -31抗体,最近被批准用于治疗狗的特应性皮炎。目前,没有其他治疗性单克隆抗体用于兽医学。这篇文献综述的目的是更新临床医生对这种新的生物选择治疗犬特应性皮炎。
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