Ping-Hsien Lee, Tori N. Yamamoto, Devikala Gurusamy, M. Sukumar, Zhiya Yu, J. Hu‐Li, T. Kawabe, Arunakumar Gangaplara, R. Kishton, A. Henning, S. Vodnala, R. Germain, W. Paul, N. Restifo
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引用次数: 48
Abstract
Lee et al. reveal that administration of IL-1β can alter the host environment to augment the magnitude and functionality of CD8+ T cells, thereby improving the efficacy of adoptively transferred tumor-reactive T cells in treating large, established tumors in mice.
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