Levels of Hemoglobin, Leukocytes, and Platelets of Chronic Kidney Disease Patients Undergoing Hemodialysis in Surabaya

M. Kahdina, N. Mardiana, D. Fauziah
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引用次数: 4

Abstract

Background: Chronic kidney disease (CKD) is increasing in Indonesia, furthermore, it requires high treatment cost such as conservative therapy and kidney transplantation or dialysis. There are two types of dialysis; hemodialysis (HD) and peritoneal dialysis. The patient who undergoes HD needs periodical laboratories evaluation due to its impact on hemoglobin (Hb), leukocyte and platelets. The purpose of this study was to obtain the levels of Hb, leukocyte and platelets regularly in stage 5 CKD patients undergoing HD.Methods: Data were collected from patients’ medical record from October to December 2014 and it was characterized based on age, sex, HD frequency, HD period, hemoglobin, iron saturation, ESA (erythropoiesis-stimulating agent), leukocyte level and platelets level. 60 samples were included with the same ratio.Results: The average of age was 45 years old and the average of HD period was 40 months. All patients suffered anemia, however, only 51 patients could be evaluated the iron saturation. From it, 37 patients had the iron saturation of ≥20% which 14 (38%) of them received ESA. There were 14 patients who suffered zinc deficiency anemia with the iron saturation of <20% which 4 (29%) of them received ESA.Conclusion: Most of patients’ leukocyte and platelets levels were normal. Patients who received ESA had higher Hb levels. Platelets levels had a reverse correlation with the longer period of hemodialysis.
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泗水接受血液透析的慢性肾病患者的血红蛋白、白细胞和血小板水平
背景:慢性肾脏疾病(CKD)在印度尼西亚呈上升趋势,并且需要较高的治疗费用,如保守治疗和肾移植或透析。透析有两种类型;血液透析(HD)和腹膜透析。由于HD对血红蛋白(Hb)、白细胞和血小板的影响,患者需要定期进行实验室评估。本研究的目的是在接受HD治疗的5期CKD患者中定期获得Hb、白细胞和血小板水平。方法:收集2014年10 - 12月患者的病历资料,根据年龄、性别、HD频次、HD病程、血红蛋白、铁饱和度、促红细胞生成素(ESA)、白细胞水平、血小板水平进行特征分析。按相同比例纳入60个样本。结果:患者平均年龄45岁,HD病程平均40个月。所有患者均出现贫血,但仅有51例患者可评估铁饱和度。37例患者铁饱和度≥20%,其中14例(38%)接受了ESA。缺锌性贫血14例,铁饱和度<20%,其中4例(29%)接受ESA治疗。结论:多数患者白细胞、血小板水平正常。接受ESA治疗的患者Hb水平较高。血小板水平与血液透析时间越长呈负相关。
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