The study of the antibacterial and antimycotic activity of nanostructures based on antibiotics, plant extracts and salts metals

A. Sirotin, A. Krolevets, V. Klyueva, Nikita Lyakhovchenko, V. Senchenkov
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Abstract

The antibacterial activity of nanostructures based on antibiotics, plant extracts and metal salts against Escherichia.coli, Staphylococcus sp. and Aspergillus niger was shown. A statistically significant increase in the inhibition effect of ceftriaxone in the poludan was shown by 33,3%, copper sulfate in Na-CMC by 121,5-562,7% depending on the ratio of core:shell and suspension concentration, birch leaf extract in Na-alginate by 36,7-86,3%, in guar gum by 110,0484,5% compared with pure preparations. The inhibitory effect from nanostructured silver nitrate was not detected. The most effective ratios are core:shell 1:1 and 1:2. Keywords—nanostructured forms; antibiotics; plant extracts; metal salts; biocidal activity
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基于抗生素、植物提取物和金属盐的纳米结构的抗菌和抗真菌活性研究
基于抗生素、植物提取物和金属盐的纳米结构对埃希氏菌的抑菌活性。大肠杆菌、葡萄球菌和黑曲霉。与纯制剂相比,头孢曲松对污染丹的抑制作用增加了33.3%,硫酸铜对钠- cmc的抑制作用增加了121,5-562,7%(取决于芯壳比和悬浮液浓度),桦叶提取物对海藻酸钠的抑制作用增加了36.7 -86,3%,瓜尔胶的抑制作用增加了110,0484,5%。未检测到纳米结构硝酸银的抑制作用。最有效的比例是核心:壳1:1和1:2。Keywords-nanostructured形式;抗生素;植物提取物;金属盐;杀生的活动
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