Pub Date : 2019-11-01DOI: 10.2991/isils-19.2019.89
E. Zhilyakova, O. Novikov, D. Pisarev, N. Boyko, K. Nikitin
the purpose of the present study was a comparative study of the ability of some freons to extract the essential oil of the roots of C. longa L. and to provide optimal conditions for its analysis. The dried, crushed roots of C. longa L. were used as raw materials (country of origin Uganda). Methoxynonafluorobutane (Novec 7100), fluoroketone and nhexane were used as extractants. Method of gas-liquid chromatography with mass detection was used. The most efficient extractant for ar-tumerone and curlone, which proved to be methoxynonafluorobutane (Novec 7100). The results of the studies indicate the prospects of using freons as extracting agents for the extraction of essential oil from the roots of C. longa L. The prospect consists in a more effective extracting ability of organofluorine solvents than n-hexane to increase the yield of both, the essential oil itself and the most pharmacologically relevant root components of C. longa L. ar-tumerone and curlone. Keywords—C. longa L. roots, ar-tumerone, curlone, methoxynonafluorobutane, fluoroketone, n-hexane.
{"title":"Prospects of Using Freons as Extractants of Curcuma Longa L. Root Essential Oil","authors":"E. Zhilyakova, O. Novikov, D. Pisarev, N. Boyko, K. Nikitin","doi":"10.2991/isils-19.2019.89","DOIUrl":"https://doi.org/10.2991/isils-19.2019.89","url":null,"abstract":"the purpose of the present study was a comparative study of the ability of some freons to extract the essential oil of the roots of C. longa L. and to provide optimal conditions for its analysis. The dried, crushed roots of C. longa L. were used as raw materials (country of origin Uganda). Methoxynonafluorobutane (Novec 7100), fluoroketone and nhexane were used as extractants. Method of gas-liquid chromatography with mass detection was used. The most efficient extractant for ar-tumerone and curlone, which proved to be methoxynonafluorobutane (Novec 7100). The results of the studies indicate the prospects of using freons as extracting agents for the extraction of essential oil from the roots of C. longa L. The prospect consists in a more effective extracting ability of organofluorine solvents than n-hexane to increase the yield of both, the essential oil itself and the most pharmacologically relevant root components of C. longa L. ar-tumerone and curlone. Keywords—C. longa L. roots, ar-tumerone, curlone, methoxynonafluorobutane, fluoroketone, n-hexane.","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75221373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.2991/isils-19.2019.17
J. Burmenko, V. Simonov, V. Vysotsky
As a result of hybridization of species: Prunus domestica L., Prunus salicina Lindl., Prunus rossica Erem., Prunus brigantina Vill., Prunus persica (L.) Batsch., Prunus armeniaca Lin., Prunus pumila L., Prunus spinosa L. crossed between Interspecific hybrids combining genomes of 2 or more species ((Prunus rossica Erem. × Prunus domestica L.) × ((Prunus pumila L. × Prunus salicina Lindl.) × Prunus spinosa L.), Prunus domestica L. × (Prunus brigantinaVill. × Prunus persica (L.) Batsch.)). Depending on the combination groups, without using the in vitro method of introducing isolated hybrid embryos into the culture, the percentage of surviving seeds varies from 0% to 15.4%. Introduction to the culture of in vitro isolated hybrid embryos on Murashige and Skoog medium with the inclusion of thidiazuron in the medium at a concentration of 1.0 mg / l for 20-23 days after pollination allows to save them from death and increase the frequency of development of adventitious shoots to 34.5 ± 4.2 % The application of this method allowed to obtain varieties ‘Tulitsa’ and ‘Velichavaya’. Keywords— Prunus, hybridization, interspecific hybrids, isolated nuclei, cultivars
结果表明:家李(Prunus domestica L.)、水杨李(Prunus salicina Lindl.)杂交。、桃李。，杨梅村。桃李(L.)类等。，杨梅。李(Prunus rossica Erem.)，李(Prunus pumila L.)，李(spinosa L.)。×李(Prunus domestica L.) × (Prunus pumila L. × Prunus salicina Lindl.) ×李(Prunus spinosa L.)，李(Prunus domestica L.) ×李(Prunus brigantinaVill.)×桃李(L.)类等)。根据组合组的不同，不使用体外方法将分离的杂交胚胎引入培养，种子存活率从0%到15.4%不等。将离体杂交胚在Murashige和Skoog培养基上以1.0 mg / l的浓度加入thidiazuron，在授粉后20-23天培养，可使其免于死亡，并使不定芽的发育率提高到34.5±4.2%。采用这种方法可获得tuitsa和Velichavaya品种。关键词:李，杂交，种间杂交，离核，栽培品种
{"title":"The Role Of Inter-Species Hybridization In Expanding The Sortiment Of Plum","authors":"J. Burmenko, V. Simonov, V. Vysotsky","doi":"10.2991/isils-19.2019.17","DOIUrl":"https://doi.org/10.2991/isils-19.2019.17","url":null,"abstract":"As a result of hybridization of species: Prunus domestica L., Prunus salicina Lindl., Prunus rossica Erem., Prunus brigantina Vill., Prunus persica (L.) Batsch., Prunus armeniaca Lin., Prunus pumila L., Prunus spinosa L. crossed between Interspecific hybrids combining genomes of 2 or more species ((Prunus rossica Erem. × Prunus domestica L.) × ((Prunus pumila L. × Prunus salicina Lindl.) × Prunus spinosa L.), Prunus domestica L. × (Prunus brigantinaVill. × Prunus persica (L.) Batsch.)). Depending on the combination groups, without using the in vitro method of introducing isolated hybrid embryos into the culture, the percentage of surviving seeds varies from 0% to 15.4%. Introduction to the culture of in vitro isolated hybrid embryos on Murashige and Skoog medium with the inclusion of thidiazuron in the medium at a concentration of 1.0 mg / l for 20-23 days after pollination allows to save them from death and increase the frequency of development of adventitious shoots to 34.5 ± 4.2 % The application of this method allowed to obtain varieties ‘Tulitsa’ and ‘Velichavaya’. Keywords— Prunus, hybridization, interspecific hybrids, isolated nuclei, cultivars","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75358473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.2991/isils-19.2019.51
N. Myachikova, O. Binkovskaya, Y. Boltenko, Irina Korotkyh
The technology of obtaining a powdered semifinished product from Pleurotus ostreatus is proposed. Assessment of the quality of the semi-finished product was made according to the organoleptic and physico-chemical indicators. Found that the share of nitrogen of soluble substances, including non-protein nitrogen and nitrogen of water-and salt-soluble protein fractions, accounts for 77.06%, and the share of nitrogen of insolu-ble substances – 22.94%. Powdered semi-finished product from mushrooms Pleurotus ostreatus are the source of complete protein, which includes 18 amino acids, including 8 essential ones. Digestibility (in vitro) of proteins of the powdered semi-finished product is 1.3 times higher than the digestibility of fresh mushrooms. Keyword—mushroom, Pleurotus ostreatus, nitrogencontaining substances, powdered semi-finished product, amino acid
{"title":"Study of Nitrogen-Containing Substances of Powdered Semi-Finished Product from Cultivated Mushrooms Pleurotus Ostreatus","authors":"N. Myachikova, O. Binkovskaya, Y. Boltenko, Irina Korotkyh","doi":"10.2991/isils-19.2019.51","DOIUrl":"https://doi.org/10.2991/isils-19.2019.51","url":null,"abstract":"The technology of obtaining a powdered semifinished product from Pleurotus ostreatus is proposed. Assessment of the quality of the semi-finished product was made according to the organoleptic and physico-chemical indicators. Found that the share of nitrogen of soluble substances, including non-protein nitrogen and nitrogen of water-and salt-soluble protein fractions, accounts for 77.06%, and the share of nitrogen of insolu-ble substances – 22.94%. Powdered semi-finished product from mushrooms Pleurotus ostreatus are the source of complete protein, which includes 18 amino acids, including 8 essential ones. Digestibility (in vitro) of proteins of the powdered semi-finished product is 1.3 times higher than the digestibility of fresh mushrooms. Keyword—mushroom, Pleurotus ostreatus, nitrogencontaining substances, powdered semi-finished product, amino acid","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78443928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.2991/isils-19.2019.67
O. Sein, Olga Tatiyanicheva, K. Mikhaĭlov, A. Shevchenko, I. Boiko, N. Maslova
The present article describes the results of the transcranial electrostimulation (TES) for the correction of blood pressure (BP) in dogs. During the experiment, systolic blood pressure (BPs), diastolic blood pressure (BPd), pulse pressure (PP), and mean blood pressure (MBP) were registered. It was established that TES mode that switched on the electrodes feeding that were fixed on the animal head at constant current (gradually increasing from 0 to 6 mA) with further switching to 75 Hz 4.0 mA square-wave pulse (impulse duration – 3.5 ms) for 30 minutes exerted corrective effect on blood pressure in dogs with pharmacologically modeled hypertension. The results of the performed tests showed that after the injection of mesatone, midodrine, and norepinephrine, the studied BP parameters elevated in all the dogs. In animals from the test groups that were injected drugs in combination with TES, the BP parameters increased insignificantly (p>0.05). In the dogs from the control groups, the increase in the BP parameters was significant in the majority of cases (p<0.05). The most significant differences between the studied parameters were observed in groups that received mesatone in combination with TES. It was revealed that after the injection of the drug and performance of TES in animals from the test group, BPs ranged within 139.7±8.8 – 146.6±8.7; BPd ranged within 78.8±6.8 – 80.0±5.0; PP – 60.0±5.8 – 67.8±5.7; MBP – 99.7±7.8 – 101.4±7.0 mmHg. In animals from the control group that did not receive TES, the parameter values were higher and ranged within 151.0±8.8 – 170.5±8.9; 80.3±6.4 – 98.9±7.3; 70.0±7.0 – 71.6±6.9; 103.9±8.0 – 122.8±8.1 mmHg, respectively. It is recommended to use TES in practical veterinary to the correction of blood pressure in dogs.
{"title":"The Influence of Transcranial Electrostimulation on Blood Pressure in Dogs with Modeled Hypertension","authors":"O. Sein, Olga Tatiyanicheva, K. Mikhaĭlov, A. Shevchenko, I. Boiko, N. Maslova","doi":"10.2991/isils-19.2019.67","DOIUrl":"https://doi.org/10.2991/isils-19.2019.67","url":null,"abstract":"The present article describes the results of the transcranial electrostimulation (TES) for the correction of blood pressure (BP) in dogs. During the experiment, systolic blood pressure (BPs), diastolic blood pressure (BPd), pulse pressure (PP), and mean blood pressure (MBP) were registered. It was established that TES mode that switched on the electrodes feeding that were fixed on the animal head at constant current (gradually increasing from 0 to 6 mA) with further switching to 75 Hz 4.0 mA square-wave pulse (impulse duration – 3.5 ms) for 30 minutes exerted corrective effect on blood pressure in dogs with pharmacologically modeled hypertension. The results of the performed tests showed that after the injection of mesatone, midodrine, and norepinephrine, the studied BP parameters elevated in all the dogs. In animals from the test groups that were injected drugs in combination with TES, the BP parameters increased insignificantly (p>0.05). In the dogs from the control groups, the increase in the BP parameters was significant in the majority of cases (p<0.05). The most significant differences between the studied parameters were observed in groups that received mesatone in combination with TES. It was revealed that after the injection of the drug and performance of TES in animals from the test group, BPs ranged within 139.7±8.8 – 146.6±8.7; BPd ranged within 78.8±6.8 – 80.0±5.0; PP – 60.0±5.8 – 67.8±5.7; MBP – 99.7±7.8 – 101.4±7.0 mmHg. In animals from the control group that did not receive TES, the parameter values were higher and ranged within 151.0±8.8 – 170.5±8.9; 80.3±6.4 – 98.9±7.3; 70.0±7.0 – 71.6±6.9; 103.9±8.0 – 122.8±8.1 mmHg, respectively. It is recommended to use TES in practical veterinary to the correction of blood pressure in dogs.","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77370559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.2991/isils-19.2019.40
Ivan Koschayev, I. Boiko, S. Kornienko, Olga Tatiyanicheva, O. Sein, S. Zdanovich, O. Popova
The article presents the results of the usage efficiency of broilers of non-conventional raw materials of vegetable dry beet pulp, which has a positive impact on the physiological characteristics of poultry and quality indicators of meat. The research was carried out at the premises of the educational and scientific poultry farm of Belgorod State Agricultural University. For the experiment, 140 daily chickens were selected and four groups (peer groups) were formed: one control group and 3 experimental groups of 35 heads each. Duration of the scientific and economic experiment – 41 days. The control group received the basic diet (BD). Chickens of all the experimental groups received the basic diet from 1 to 20 days. In 21-41 days, chickens of the 1st experimental group were fed 98% BD and 2% of the dry pulp, 2nd group – 96% BD and 4% of dry pulp, while 3d experimental group – 95% BD and 5% of dry pulp. As a result of the research, it was found that the use of dry beet pulp (replacement of 4% BD) in the diets of broiler chickens has a positive impact on their productivity and the quality of meat products. When it is included in the diet, the feed costs per unit of output are reduced. By replacing the basic diet with dry pulp, the authors significantly reduce the cost of feed, which leads to an increase in profitability by 4.7%. Keywords—Broiler chickens, dry beet pulp, live weight, efficiency, meat quality
{"title":"Feeding Efficiency of Dry Beet Pulp to Broiler Chickens","authors":"Ivan Koschayev, I. Boiko, S. Kornienko, Olga Tatiyanicheva, O. Sein, S. Zdanovich, O. Popova","doi":"10.2991/isils-19.2019.40","DOIUrl":"https://doi.org/10.2991/isils-19.2019.40","url":null,"abstract":"The article presents the results of the usage efficiency of broilers of non-conventional raw materials of vegetable dry beet pulp, which has a positive impact on the physiological characteristics of poultry and quality indicators of meat. The research was carried out at the premises of the educational and scientific poultry farm of Belgorod State Agricultural University. For the experiment, 140 daily chickens were selected and four groups (peer groups) were formed: one control group and 3 experimental groups of 35 heads each. Duration of the scientific and economic experiment – 41 days. The control group received the basic diet (BD). Chickens of all the experimental groups received the basic diet from 1 to 20 days. In 21-41 days, chickens of the 1st experimental group were fed 98% BD and 2% of the dry pulp, 2nd group – 96% BD and 4% of dry pulp, while 3d experimental group – 95% BD and 5% of dry pulp. As a result of the research, it was found that the use of dry beet pulp (replacement of 4% BD) in the diets of broiler chickens has a positive impact on their productivity and the quality of meat products. When it is included in the diet, the feed costs per unit of output are reduced. By replacing the basic diet with dry pulp, the authors significantly reduce the cost of feed, which leads to an increase in profitability by 4.7%. Keywords—Broiler chickens, dry beet pulp, live weight, efficiency, meat quality","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85221844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.2991/isils-19.2019.23
Lyudmila Efremencko, A. Malyutina, D. Pisarev, Valentina Scorbach, N. Shestopalova, Valentina Kasakova, D. Fadeeva
The aim of this work is phytochemical studies and standardization of Scabiosa succisa L. By reverse phase high performance liquid chromatography of ethanol extract substances belonging to polyphenolic compounds were found, among which hydroxycinnamic acids predominate. Chlorogenic acid and flavonoid glycosides of apigenin and luteolin were identified. Microscopic analysis revealed the main diagnostic features of the Scabiosa succisa L. herb. As a result of research component composition of Scabiosa succisa L. polyphenols was partially installed, which substantiates its anti-inflammatory properties, and microdiagnostics signs were discovered, which can determine the plant authenticity. Keywords—Scabiosa succisa L., Caprifoliaceae, standardization, high-performance liquid chromatography, microscopy, phenolic compounds
{"title":"Phytochemical Studies and Standardization of Scabiosa Succisa L.","authors":"Lyudmila Efremencko, A. Malyutina, D. Pisarev, Valentina Scorbach, N. Shestopalova, Valentina Kasakova, D. Fadeeva","doi":"10.2991/isils-19.2019.23","DOIUrl":"https://doi.org/10.2991/isils-19.2019.23","url":null,"abstract":"The aim of this work is phytochemical studies and standardization of Scabiosa succisa L. By reverse phase high performance liquid chromatography of ethanol extract substances belonging to polyphenolic compounds were found, among which hydroxycinnamic acids predominate. Chlorogenic acid and flavonoid glycosides of apigenin and luteolin were identified. Microscopic analysis revealed the main diagnostic features of the Scabiosa succisa L. herb. As a result of research component composition of Scabiosa succisa L. polyphenols was partially installed, which substantiates its anti-inflammatory properties, and microdiagnostics signs were discovered, which can determine the plant authenticity. Keywords—Scabiosa succisa L., Caprifoliaceae, standardization, high-performance liquid chromatography, microscopy, phenolic compounds","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84066227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.2991/isils-19.2019.77
I. Spichak, O. Vladimirova, I. Zhirova
The article presents the results of the optimization of the drug supply for children with disorders of the autonomic nervous system (ANS) under inpatient treatment at the regional level; a socio-demographic portrait of a child affected with autonomic dysfunction syndrome has been developed; a pharmacoeconomic study of the drug assortment prescribed in the hospital has been conducted; a formulary list of drugs has been formed. Keywords— drug provision, autonomic dysfunction syndrome in children, formulary list, pharmacoeconomic study
{"title":"Optimization of Drug Provision for Children with Diseases of Autonomic Nervous System under Inpatient Treatment","authors":"I. Spichak, O. Vladimirova, I. Zhirova","doi":"10.2991/isils-19.2019.77","DOIUrl":"https://doi.org/10.2991/isils-19.2019.77","url":null,"abstract":"The article presents the results of the optimization of the drug supply for children with disorders of the autonomic nervous system (ANS) under inpatient treatment at the regional level; a socio-demographic portrait of a child affected with autonomic dysfunction syndrome has been developed; a pharmacoeconomic study of the drug assortment prescribed in the hospital has been conducted; a formulary list of drugs has been formed. Keywords— drug provision, autonomic dysfunction syndrome in children, formulary list, pharmacoeconomic study","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77982187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.2991/isils-19.2019.80
A. Trchounian
The development of clean alternative biofuel, including biohydrogen, is of great significant interest. One method for biohydrogen is dark and light fermentation when hydrogenases are responsible enzymes for H2 metabolism. A further development of biotechnology for H2 production can be directed in the following ways at least: construction or selection of appropriate effective bacterial strains (mutants) and cultures; creation of mixed cultures; application of different carbon sources (sugars, alcohols and organic acids) and their mixtures for co-fermentation as well as organic wastes (glycerol and lignocellulose waste); control of external technology factors (pH, redox potential, substrate concentration), addition of different compounds and their mixtures, especially some heavy metals (Ni, Fe, Mo, Mg, Cu, etc). Biohydrogen has of interest when was producing with bioethanol. It can also be applied for enhanced production of biomethane. Keywords—biotechnology for biofuel, hydrogen energy, biomethane, fermentation, bacteria
{"title":"Prospective Trends in Biotechnology for Biofuel","authors":"A. Trchounian","doi":"10.2991/isils-19.2019.80","DOIUrl":"https://doi.org/10.2991/isils-19.2019.80","url":null,"abstract":"The development of clean alternative biofuel, including biohydrogen, is of great significant interest. One method for biohydrogen is dark and light fermentation when hydrogenases are responsible enzymes for H2 metabolism. A further development of biotechnology for H2 production can be directed in the following ways at least: construction or selection of appropriate effective bacterial strains (mutants) and cultures; creation of mixed cultures; application of different carbon sources (sugars, alcohols and organic acids) and their mixtures for co-fermentation as well as organic wastes (glycerol and lignocellulose waste); control of external technology factors (pH, redox potential, substrate concentration), addition of different compounds and their mixtures, especially some heavy metals (Ni, Fe, Mo, Mg, Cu, etc). Biohydrogen has of interest when was producing with bioethanol. It can also be applied for enhanced production of biomethane. Keywords—biotechnology for biofuel, hydrogen energy, biomethane, fermentation, bacteria","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72804785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.2991/isils-19.2019.65
N. Sahakyan, M. Petrosyan, I. Batlutskaya, A. Trchounian
In the recent years there is a growing demand for plant origin antioxidants, due to their potential therapeutic value and low level of side effects. Among the plant origin substances, the metabolites with antioxidant activity are the widely used which are mainly belong to the phenolic group of compounds as well as carotenoids and vitamins. These natural antioxidants act via different mechanisms: they can decrease the level of oxidative damage in cells directly reacting with free radicals or indirectly by inhibition the activity and expression of free radical generating enzymes or enhancing the activity or expression of intracellular antioxidant defense enzymes. The manuscript is focused on the main group of phenolics which can be used in pharmacological, food and other areas. Keywords—antioxidants, plant born metabolites, phenolics,
{"title":"Plant Origin Phenolics as Prospective Antioxidants: State-of-Art for Application","authors":"N. Sahakyan, M. Petrosyan, I. Batlutskaya, A. Trchounian","doi":"10.2991/isils-19.2019.65","DOIUrl":"https://doi.org/10.2991/isils-19.2019.65","url":null,"abstract":"In the recent years there is a growing demand for plant origin antioxidants, due to their potential therapeutic value and low level of side effects. Among the plant origin substances, the metabolites with antioxidant activity are the widely used which are mainly belong to the phenolic group of compounds as well as carotenoids and vitamins. These natural antioxidants act via different mechanisms: they can decrease the level of oxidative damage in cells directly reacting with free radicals or indirectly by inhibition the activity and expression of free radical generating enzymes or enhancing the activity or expression of intracellular antioxidant defense enzymes. The manuscript is focused on the main group of phenolics which can be used in pharmacological, food and other areas. Keywords—antioxidants, plant born metabolites, phenolics,","PeriodicalId":20489,"journal":{"name":"Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86811960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.2991/isils-19.2019.14
G. Brkich, N. Pyatigorskaya, A. Nedorubov, O. Filippova, O. Zyryanov
The aim of this study was to develop the effect of substance Z–109 a bicyclononan derivative, presumably belonging to the class of ampakines on the memory of rats undergoing cerebral ischemia. The evaluation of mnestic functions was carried out on the model of the conditioned passive avoidance reflex. Ischemic brain damage was reproduced by 200 in rats of both sexes occlusion of the middle cerebral artery, photoinduced thrombosis in the prefrontal cortex, complete ligation of both carotid arteries. The test substance was found to have a positive effect at doses of 2.5 mg / kg, 13 mg/kg and 25 mg / kg in the treatment of various types of ischemic brain damage, the substance had a maximum effect at a dose of 2.5 mg / kg. The investigated substance is possible for prospective study as a neuroprotective anti-stroke agent.
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