Transient Simulation of Field-Effect Biosensors How to Avoid Charge Screening Effect

Kyoung Yeon Kim, Byung-Gook Park
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Abstract

We developed a numerical simulator to model the operation of a bio-FET in transient state. The simulator takes a realistic device structure as a simulation domain, and it employs the drift-diffusion equation for ion/ channel transport, and the Ramo-Shockley theorem for accurate calculation of non- faradaic current. For efficient transient simulation, the implicit time integration scheme is employed where the solution at each time step is obtained from the coupled Newton-Raphson method. Using the simulator, we found that the sensitivity of bio- FET can be improved with transient measurement by redistribution of the mobile ions by an external electric field.
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场效应生物传感器瞬态仿真如何避免电荷筛选效应
我们开发了一个数值模拟器来模拟生物场效应管的瞬态工作。该模拟器以实际器件结构为模拟域,采用离子/通道输运的漂移-扩散方程,利用Ramo-Shockley定理精确计算非法拉第电流。为了有效地进行瞬态仿真,采用隐式时间积分方法,利用耦合Newton-Raphson方法求得各时间步的解。利用该模拟器,我们发现利用外电场重新分配可移动离子的瞬态测量可以提高生物场效应管的灵敏度。
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