Qin Zhou, Soobhug Rishikesh Singh, Soobhug Shalini Devi Tina, J. Wena, Zhou Yiying, S. Mac, R. Mariella
{"title":"The Pathways in Endometrial Carcinogenesis and an Overview of its Histology, Grade and Stage","authors":"Qin Zhou, Soobhug Rishikesh Singh, Soobhug Shalini Devi Tina, J. Wena, Zhou Yiying, S. Mac, R. Mariella","doi":"10.21767/2386-5180.1000231","DOIUrl":null,"url":null,"abstract":"Endometrial carcinoma is the most common female genital tract cancer in the developed countries. It is classified as Type I and II endometrial cancer. Understanding of the pathogenesis of each type plays a pivotal role in identifying their precursors. The histological subtype, grade and stage guide the treatment strategies and portend the prognosis in endometrial carcinoma. Hysterectomy is regarded curative in early stage disease. By contrast, uterine serous carcinoma is the most aggressive histologic subtype associated with a low 5-year overall survival rate. Substantial rise in uterine corpus carcinoma parallels with the increase in obesity and diabetes. As they share similar etiologies, measures can be adopted to tackle the modifiable risk factors. No screening consensus is available for low or average risk populations.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"91 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Clinical and Laboratory Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21767/2386-5180.1000231","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Endometrial carcinoma is the most common female genital tract cancer in the developed countries. It is classified as Type I and II endometrial cancer. Understanding of the pathogenesis of each type plays a pivotal role in identifying their precursors. The histological subtype, grade and stage guide the treatment strategies and portend the prognosis in endometrial carcinoma. Hysterectomy is regarded curative in early stage disease. By contrast, uterine serous carcinoma is the most aggressive histologic subtype associated with a low 5-year overall survival rate. Substantial rise in uterine corpus carcinoma parallels with the increase in obesity and diabetes. As they share similar etiologies, measures can be adopted to tackle the modifiable risk factors. No screening consensus is available for low or average risk populations.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
