{"title":"Synthesis and physico-chemical characterization of some novel oxazepine derivatives","authors":"L. Joseph, M. George, Surekha","doi":"10.7439/IJPC.V6I11.3713","DOIUrl":null,"url":null,"abstract":"Series of oxazepine derivatives were synthesized from Schiffs base as aldehyde derivatives by using semicarbazide as starting material.Then equimolar quantities of prepared Schiffs base reacts with pthallic anhydride or succinic anhydride undergo cycloaddition reaction in the presence of organic solvent benzene give an oxazepine ring system. Chemical structures of the synthesized compounds were confirmed on the basis of their spectral data","PeriodicalId":14317,"journal":{"name":"International Journal of Pharmaceutical Chemistry","volume":"87 1","pages":"224-229"},"PeriodicalIF":0.0000,"publicationDate":"2016-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pharmaceutical Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7439/IJPC.V6I11.3713","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Series of oxazepine derivatives were synthesized from Schiffs base as aldehyde derivatives by using semicarbazide as starting material.Then equimolar quantities of prepared Schiffs base reacts with pthallic anhydride or succinic anhydride undergo cycloaddition reaction in the presence of organic solvent benzene give an oxazepine ring system. Chemical structures of the synthesized compounds were confirmed on the basis of their spectral data
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