Night Shift Work Accelerates Menopausal Age in Health Workers

S. Dwiningsih, Samsulhadi Samsulhadi, Arif Tunjungseto, Monika Lijuwardi, Arsana Wiyasa
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Abstract

Introduction: Earlier menopause has been associated with increased risk of cardiovascular disease, osteoporosis, shorter life expectancy and even cognitive decline. There are many factors that cause differences in the age of menopause in women, one of these environmental factors is a history of night shift work as a consequence of a job. It is not yet known whether female medical workers, with a history of night shifts, get earlier menopause.Methods: This case control study was conducted among 57 female night workers of the Dr. Soetomo General Academic Hospital. Data collection was conducted from December 2019 - March 2020. The study sample was postmenopausal health workers (nurse and midwife) and administrators. The instrument used in this study was a list of interview questions. The data was processed using SPSS software release 23.Results: The results show that from 45 children diagnosed with ALL, 53% are of the age ≤ 5 years old, with 58% males and 42% females. 13% of the patients are in the high risk group and 87% are in the standard risk group. Nutritional statuses of patients are 2% of them obese experienced remission after induction phase therapy, 56% normal with 80% of them experienced remission. 40% underweight with 89% of them experienced remission and 11% not experienced remission, 2% malnutrition and experienced remission. There is no correlation between the nutritional status of children with acute lymphoblastic leukemia with the outcome of induction phase (p = 0.798).Conclusion: In conclusion, there is no correlation between nutritional status and remission outcome of patients with ALL in the induction phase of therapy. However, high percentage of underweight patients shows nutrition needs special attention to improve therapy outcomes. 
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夜班工作加速卫生工作者的绝经年龄
引言:提前绝经与心血管疾病、骨质疏松、预期寿命缩短甚至认知能力下降的风险增加有关。造成女性更年期年龄差异的因素有很多,其中一个环境因素是由于工作原因而导致的夜班工作的历史。有夜班史的女性医务工作者是否会提前绝经,目前尚不清楚。方法:以苏托莫博士综合学术医院57名女夜班工人为研究对象进行病例对照研究。数据收集时间为2019年12月至2020年3月。研究样本为绝经后卫生工作者(护士和助产士)和行政人员。本研究使用的工具是一个访谈问题列表。数据采用SPSS软件第23版进行处理。结果:45例ALL患儿中,年龄≤5岁的占53%,其中男性占58%,女性占42%。13%的患者属于高危组,87%的患者属于标准危险组。患者营养状况:诱导期治疗后肥胖患者缓解率为2%,正常患者56%,缓解率为80%。40%的人体重过轻,89%的人缓解,11%的人没有缓解,2%的人营养不良,也有缓解。急性淋巴细胞白血病患儿营养状况与诱导期结局无相关性(p = 0.798)。结论:综上所述,ALL患者在治疗诱导期的营养状况与缓解结果无相关性。然而,高比例的体重不足患者需要特别注意营养以改善治疗效果。
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