Ly49E separates liver ILC1s into embryo-derived and postnatal subsets with different functions

Yawen Chen, Xianwei Wang, Xiaolei Hao, Bin Li, Wanyin Tao, Shu Zhu, K. Qu, Haiming Wei, R. Sun, Hui Peng, Z. Tian
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引用次数: 17

Abstract

Chen et al. uncovered the transcriptional, developmental, and functional heterogeneity of ILC1s and demonstrated the dynamic changes that occur in ILC1 subsets from different origins during ontogeny, which correspond to their different functional roles, facilitating adaptation to age-related immune demands.
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Ly49E将肝脏ILC1s分离为胚胎源性和出生后的不同功能亚群
Chen等人揭示了ILC1的转录、发育和功能异质性,并证明了不同来源的ILC1亚群在个体发育过程中发生的动态变化,这些变化对应于它们不同的功能角色,促进了对年龄相关免疫需求的适应。
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