Evaluation of in vitro antibacterial activity of Carum copticum extract against drug resistant Staphylococcus aureus from clinical and food sources

J. Khan, R. Rathore, Iqbal Ahmad, Rubina Gill, F. Husain, Javeed Akhtar, L. D. Tolesa, Misbahu Abdu Ayanso, Mekonnen Begna
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Abstract

Staphylococcus aureus is commensal and human pathogen both. The bacterium is one of the most common causes of food borne infections also in all over the world. C. copticum (Ajwain) is an aromatic spice used as a medicinal plant from ancient time for treating different human diseases including infectious diseases. The highest anti-staphylococcal activity in terms of inhibition zone was recorded 18.5 mm whereas 14.5 mm as lowest. The MIC range of ethanolic extract was evaluated amid 1.56 mg/ml to 3.12 mg/ml. The C. copticum (seed) extract might be useful as anti-staphylococcal agent as well as natural food preservative.
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黄连提取物对临床和食物来源的耐药金黄色葡萄球菌的体外抗菌活性评价
金黄色葡萄球菌是共生的和人类病原体兼有。这种细菌是世界上最常见的食源性感染原因之一。黄连是一种芳香香料,自古以来就被用作药用植物,用于治疗包括传染病在内的各种人类疾病。抑菌区抗葡萄球菌活性最高为18.5 mm,最低为14.5 mm。乙醇提取物的MIC范围为1.56 ~ 3.12 mg/ml。黄连(种子)提取物可作为抗葡萄球菌剂和天然食品防腐剂。
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