A Comparative Study of Theophylline Preparations: Digestive Absorption*

Abstract

Six theophylline preparations have been tested for their absorption from the gastrointestinal tracts of animals as reflected by blood theophylline levels. These values were obtained first from the stomach, and then from the remainder of the gastrointestinal tract. The results showed satisfactory absorption with all medications, and the wide variation inherent in oral preparations. No real superiority was evident in the six preparations when the available theophylline was the same in each drug.