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Journal of the American Pharmaceutical Association (Scientific ed.)最新文献

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Symposium on antibiotics 抗生素研讨会
Journal of the American Pharmaceutical Association (Scientific ed.)
Pub Date : 1963-01-01 DOI: 10.1002/jps.3030450612
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引用次数: 0
Prediction of stability in pharmaceutical preparations VII. The solution degradation of the antibiotic streptozotocin 药物制剂稳定性的预测7。抗生素链脲佐菌素的溶液降解
Journal of the American Pharmaceutical Association (Scientific ed.)
Pub Date : 1960-12-01 DOI: 10.1002/jps.3030491208
Edward R. Garrett

The kinetics of solution degradation of the antibiotic streptozotocin have been studied polarographically, spectrophotometrically, and by bioassay. Equations have been obtained to characterize degradation as a function of pH, buffer, and temperature. Bioassay has been correlated with these others and correction procedures devised to account for their limitations. Stability in vitro and in vivo has been predicted. A mechanism is proposed that accounts for the available data and describes the weakly basic nature of streptozotocin and indicates the presence of a N-nitro-somethylurea function in the antibiotic.

用极谱法、分光光度法和生物测定法研究了抗生素链脲佐菌素的溶液降解动力学。已经得到了描述降解作为pH、缓冲液和温度的函数的方程。生物测定法与其他方法相关联，并设计了纠正程序来解释其局限性。体外和体内的稳定性已被预测。提出了一种机制，该机制解释了现有数据，描述了链脲佐菌素的弱碱性，并表明抗生素中存在n -硝基-somethylurea功能。
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引用次数: 33
Pharmakologie. By Von Knud O. Møller. Benno Schwabe & Co., Verlag, Basel, Stuttgart, 1958. Available in the U. S. from Intercontinental Medical Book Corp., 381 Fourth Ave., New York 16, N. Y. 902 pp. 17 × 24.5 cm 药物学。Von Knud O. Møller 著。Benno Schwabe & Co., Verlag, Basel, Stuttgart, 1958 年。美国洲际医学图书公司（Intercontinental Medical Book Corp., 381 Fourth Ave.17 × 24.5 厘米
Journal of the American Pharmaceutical Association (Scientific ed.)
Pub Date : 1960-12-01 DOI: 10.1002/jps.3030491213
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引用次数: 0
General endocrinology. 3rd ed. By C. Donnell Turner. W. B. Saunders Co., West Washington Square, Philadelphia 5, Pa., 1960. xi + 511 pp. 15.5 × 23.5 cm. Price $9.50 普通内分泌学》。第 3 版，C. Donnell Turner 著。W. B. Saunders Co., West Washington Square, Philadelphia 5, Pa., 1960. xi + 511 pp.15.5 × 23.5 厘米。售价 9.50 美元
Journal of the American Pharmaceutical Association (Scientific ed.)
Pub Date : 1960-12-01 DOI: 10.1002/jps.3030491214
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引用次数: 0
British veterinary codex supplement 1959. Published by direction of the Council of the Pharmaceutical Society of Great Britain. The Pharmaceutical Press, London, 1959. Obtainable in the U. S. from Rittenhouse Book Store, 1706 Rittenhouse Square, Philadelphia 3, Pa. xviii + 134 pp. 14.5 × 22.5 cm. price $6 英国兽医法典增刊1959。由英国药学会理事会指示出版。医药出版社，伦敦，1959年。可在美国从里滕豪斯书店买到，1706里滕豪斯广场，费城3，宾夕法尼亚州。Xviii + 134页。14.5 × 22.5厘米。价格6美元
Journal of the American Pharmaceutical Association (Scientific ed.)
Pub Date : 1960-12-01 DOI: 10.1002/jps.3030491222
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引用次数: 0
Advanced organic chemistry. 3rd ed. By G. W. Wheland. John Wiley & Sons, Inc., 440 Fourth Ave., New York 16, N. Y., 1960. xi + 871 pp. 15 × 23 cm. Price $17.50 高级有机化学》。第 3 版，G. W. Wheland 著。John Wiley & Sons, Inc., 440 Fourth Ave., New York 16, N. Y., 1960. xi + 871 pp.15 × 23 厘米。售价 17.50 美元
Journal of the American Pharmaceutical Association (Scientific ed.)
Pub Date : 1960-12-01 DOI: 10.1002/jps.3030491220
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引用次数: 0
Chemotherapy in emotional disorders. By Frederic F. Flach and Peter F. Regan. McGraw-Hill Book Co., Inc., 330 West 42nd St., New York 36, N. Y., 1960. xiv + 314 pp. 15 × 23 cm. Price $10 情绪障碍的化疗。作者:Frederic F. Flach和Peter F. Regan。麦格劳-希尔图书有限公司，西42街330号，纽约36,n.y.， 1960。14 + 314页。15 × 23厘米。价格10美元
Journal of the American Pharmaceutical Association (Scientific ed.)
Pub Date : 1960-12-01 DOI: 10.1002/jps.3030491225
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引用次数: 0
Biochemical preparations. Vol. 7. Edited by Henry A. Lardy. John Wiley & Sons. Inc., 440 Fourth Ave., New York 16, N. Y., 1960. ix + 102 pp. 15 × 23 cm. Price $5.25 生化制剂》第 7 卷。第 7 卷，Henry A. Lardy 编辑。John Wiley & Sons.Inc., 440 Fourth Ave., New York 16, N. Y., 1960. ix + 102 pp.15 × 23 厘米。售价 5.25 美元
Journal of the American Pharmaceutical Association (Scientific ed.)
Pub Date : 1960-12-01 DOI: 10.1002/jps.3030491224
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引用次数: 0
Note on the synthesis of dihydroresorcinol 二氢间苯二酚的合成说明
Journal of the American Pharmaceutical Association (Scientific ed.)
Pub Date : 1960-12-01 DOI: 10.1002/jps.3030491212
Bernhard Esch, Howard J. Schaeffer
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引用次数: 3
Metabolic and morphological changes induced by gibberellic acid on spearmint 赤霉素酸对绿薄荷代谢和形态的影响
Journal of the American Pharmaceutical Association (Scientific ed.)
Pub Date : 1960-12-01 DOI: 10.1002/jps.3030491211
Edward E. Gonzalez, Gunnar Gjerstad

The influence of gibberellic acid on the growth of spearmint and on the production of the volatile oil has been studied. Spearmint plants treated once throughout their growth period with foliar sprays of gibberellic acid in a concentration of 50 p. p. m. displayed a 258 per cent increase in linear growth. The experimental plants developed a very thick, wood-like stem which had an extended xylem region and missing ribs. An increase in dry matter and a decrease in water content of the tissues were found. Gibberellic acid treatment decreased percentagewise the amount of volatile oil but did not alter its carvone content. The oil met all N. F. standards. A decrease in total chlorophyll content was found.

研究了赤霉素酸对绿薄荷生长和挥发油产量的影响。留山薄荷植物在其整个生长期用浓度为50 ppm的赤霉素酸叶面喷雾处理一次，其线性生长增加了258%。实验植物发育出非常粗的、像木头一样的茎，它有延伸的木质部区域和缺失的肋骨。干物质增加，组织含水量减少。赤霉素处理使挥发油含量按百分比下降，但对香芹酮含量没有影响。这些油符合美国原子能机构的所有标准。总叶绿素含量下降。
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引用次数: 4
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