Evaluation of Adiponectin and Hepcidin with some Biochemical Parameters in Sera of Women with Polycystic Ovary Syndrome

S. Kadhim, F. Al-Fartusie, N. Klichkhanov
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Abstract

Polycystic ovarian syndrome (PCOS) is the most recorded endocrinological condition that impacts women throughout their fertile years and causes a variety of clinical symptoms. The study included 60 women with PCOS and 60 women who were matched for age and body mass index (BMI) and excluded the participants refrain from vigorous exercise and drink anything with alcohol or caffeine. were tested levels for IR, insulin, Hepcidin, Adiponectin, lipids profile in control and PCOS. and found Reduced levels (non sig.) of adiponectin have been documented in Iraqi patients with Polycystic Ovary Syndrome. There was an inverse relationship between IR and hepcidin levels in both groups meaning increase in IR (0.001) and decrease in hepcidin (0.001) levels may increase the risk of PCOS. well found that lipid profile (HDL, LDL, TG) that is non-significant but cholesterol high significant 0.001 in patients.  
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多囊卵巢综合征妇女血清脂联素、Hepcidin及一些生化指标的评价
多囊卵巢综合征(PCOS)是记录最多的内分泌疾病,影响妇女整个生育期,并引起各种临床症状。该研究包括60名患有多囊卵巢综合征的女性和60名年龄和体重指数(BMI)相符的女性,并排除了不进行剧烈运动和饮用任何含酒精或咖啡因的饮料的参与者。检测IR、胰岛素、Hepcidin、脂联素、对照组和多囊卵巢综合征的血脂水平。发现在伊拉克患有多囊卵巢综合征的患者中脂联素水平降低(无迹象)。在两组中,IR和hepcidin水平呈负相关,这意味着IR升高(0.001)和hepcidin降低(0.001)可能增加PCOS的风险。我们发现患者的脂质谱(HDL, LDL, TG)不显著,但胆固醇高显著0.001。
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