Antenatal transabdominal amnio‐infusion for oligo‐hydramnios due to preterm premature rupture of membranes

T. Tan, A. Tan
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Abstract

A reduction in the amount of amniotic fluid occurs in 3–5% of all deliveries. This could be due to congenital anomalies, IUGR or premature rupture of membranes. Preterm rupture of membranes places the fetus at risk of cord compression and amnionitis. On the other hand, oligo‐hydramnios has been associated with severe pulmonary hypoplasia. In 1983, Miyazaki and Nevarez first reported the effectiveness of intrauterine installation of saline solutions in relieving variable decelerations during labor. Since then, amnio‐infusion has aroused interest. To our knowledge, there has been no conclusive study done to evaluate the use of antenatal amnio‐infusion for oligo‐hydramnios diagnosed antenatally. We would like to present three case‐studies of oligo‐hydramnios seen in our department in the period 1997–2001 which we performed antenatal transabdominal amnio‐infusion. Warm saline/Hartmann solution was injected through a 22G spinal needle under ultrasound guidance. Vaginal delivery occurred in two cases (one term and one preterm); the third pregnancy is still on‐going. There was no meconium aspiration and no signs of fetal distress. Both cases had good maternal and neonatal outcome except that the preterm baby was treated with intravenous ampicillin/gentamicin for pneumonia. There was no congenital malformation noted.
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产前经腹羊膜输注治疗因胎膜早破引起的羊水过少
羊水量减少发生在所有分娩的3-5%。这可能是由于先天性异常,IUGR或胎膜过早破裂。胎膜过早破裂使胎儿有脐带受压和羊膜炎的危险。另一方面,羊水过少与严重的肺发育不全有关。1983年,Miyazaki和Nevarez首次报道了宫内放置生理盐水溶液缓解分娩过程中可变减速的有效性。从那时起,羊膜输注引起了人们的兴趣。据我们所知,目前还没有结论性的研究来评估产前羊水输注对产前诊断的羊水过少的应用。我们将介绍1997-2001年期间在我科进行产前经腹羊膜输注的羊水过少的三个病例研究。在超声引导下通过22G脊髓针注射温生理盐水/Hartmann溶液。阴道分娩2例(1例足月和1例早产);第三次怀孕仍在进行中。没有吸粪,也没有胎儿窘迫的迹象。除了早产儿因肺炎接受静脉注射氨苄西林/庆大霉素治疗外,这两例均有良好的产妇和新生儿结局。没有发现先天性畸形。
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