OC072: Assessment of endometrial and ovarian characteristics using 3‐D power Doppler ultrasound to predict response in frozen embryo transfer cycles

T. Žáčková, T. Žáčková, I. Järvelä
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引用次数: 1

Abstract

Objectives: To evaluate whether endometrial or ovarian parameters as measured using 3-D power Doppler ultrasound can predict the outcome in frozen embryo transfer (FET) cycles. Methods: 30 women with no known gynecological pathology (e.g. endometriosis, fibroids, any operation to gynecological organs) undergoing FET were recruited. FET was carried out in natural menstrual cycle 3–4 days after the first positive LH test result. A transvaginal 3-D ultrasound examination (Voluson Expert 730, Kretz Zipf, Austria) was performed on the day of FET and repeated about one week later, at the time of expected implantation. The outcome measures were endometrial pattern, thickness, volume, vascularization index (VI), subendometrial volume and VI, dominant and non-dominant ovarian volume and VI. The subendometrial region was considered to be 5 mm beneath the border between endometrium and myometrium. At the second visit no power Doppler was used to examine the endometrium. Results: The demographic, clinical and embryological characteristic were similar between pregnant (15/30) and nonpregnant groups (15/30) (Table). There were no differences between the groups in endometrial/subendometrial thickness, volume or VI. The endometrial triple line pattern was more often present in the pregnant group on the day of FET (93.3% vs. 40.0%, 95% CI 25.5–81.2%). No differences in the ovaries were observed on the day of FET (Table). At the second visit the triple line pattern was also more often present in those patients who conceived (91.7% vs. 42.9%, 95% CI 18.5–79.1%), but still no differences were observed in the dominant ovarian vasculature (Table). Conclusions: According to our results, measurement of power Doppler indices using 3-D ultrasound on the day of FET does not provide us any additional information concerning the outcome of the cycle. The existence of triple line pattern on the day of FET seems to be prognostic sign of a prosperous outcome after FET.
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OC072:使用三维功率多普勒超声评估子宫内膜和卵巢特征以预测冷冻胚胎移植周期的反应
目的:评价三维功率多普勒超声测量子宫内膜或卵巢参数是否可以预测冷冻胚胎移植(FET)周期的结局。方法:选取30例未见妇科病理(如子宫内膜异位症、子宫肌瘤、任何妇科器官手术)的女性进行FET手术。在首次LH阳性后的自然月经周期3-4天进行FET。在FET当天进行经阴道三维超声检查(Voluson Expert 730, Kretz Zipf, Austria),并在大约一周后预期植入时重复检查。结果测量为子宫内膜形态、厚度、体积、血管化指数(VI)、子宫内膜下体积和VI、优势和非优势卵巢体积和VI。子宫内膜下区域被认为是子宫内膜和子宫肌层之间边界以下5mm。在第二次就诊时,未使用功率多普勒检查子宫内膜。结果:妊娠组(15/30)和非妊娠组(15/30)的人口学、临床和胚胎学特征相似(表)。各组间子宫内膜/子宫内膜下厚度、体积或VI均无差异。子宫内膜三线模式在妊娠组FET当天更为常见(93.3% vs. 40.0%, 95% CI 25.5-81.2%)。FET当天卵巢未见差异(表)。在第二次就诊时,怀孕的患者也更常出现三线模式(91.7%对42.9%,95% CI 18.5-79.1%),但在优势卵巢脉管系统中仍未观察到差异(表)。结论:根据我们的研究结果,在FET当天使用三维超声测量功率多普勒指数并没有为我们提供任何关于周期结果的额外信息。三线模式在FET当天的存在似乎是FET后预后良好的预兆。
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OP16.13: Clinical combining‐application of ultrasound and MRI on multiplets malformations P37.08: Twin reversed arterial perfusion (TRAP) sequence: Case report of conservative management and good pregnancy outcome OC072: Assessment of endometrial and ovarian characteristics using 3‐D power Doppler ultrasound to predict response in frozen embryo transfer cycles OP03.18: Brain echogenicities in fetuses at risk for preterm birth P20.09: Three‐dimensional sonographic assessment of septate uterus before and after hysteroscopic metroplasty
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