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OC072: Assessment of endometrial and ovarian characteristics using 3‐D power Doppler ultrasound to predict response in frozen embryo transfer cycles OC072:使用三维功率多普勒超声评估子宫内膜和卵巢特征以预测冷冻胚胎移植周期的反应
Pub Date : 2008-08-01 DOI: 10.1002/UOG.5480
T. Žáčková, T. Žáčková, I. Järvelä
Objectives: To evaluate whether endometrial or ovarian parameters as measured using 3-D power Doppler ultrasound can predict the outcome in frozen embryo transfer (FET) cycles. Methods: 30 women with no known gynecological pathology (e.g. endometriosis, fibroids, any operation to gynecological organs) undergoing FET were recruited. FET was carried out in natural menstrual cycle 3–4 days after the first positive LH test result. A transvaginal 3-D ultrasound examination (Voluson Expert 730, Kretz Zipf, Austria) was performed on the day of FET and repeated about one week later, at the time of expected implantation. The outcome measures were endometrial pattern, thickness, volume, vascularization index (VI), subendometrial volume and VI, dominant and non-dominant ovarian volume and VI. The subendometrial region was considered to be 5 mm beneath the border between endometrium and myometrium. At the second visit no power Doppler was used to examine the endometrium. Results: The demographic, clinical and embryological characteristic were similar between pregnant (15/30) and nonpregnant groups (15/30) (Table). There were no differences between the groups in endometrial/subendometrial thickness, volume or VI. The endometrial triple line pattern was more often present in the pregnant group on the day of FET (93.3% vs. 40.0%, 95% CI 25.5–81.2%). No differences in the ovaries were observed on the day of FET (Table). At the second visit the triple line pattern was also more often present in those patients who conceived (91.7% vs. 42.9%, 95% CI 18.5–79.1%), but still no differences were observed in the dominant ovarian vasculature (Table). Conclusions: According to our results, measurement of power Doppler indices using 3-D ultrasound on the day of FET does not provide us any additional information concerning the outcome of the cycle. The existence of triple line pattern on the day of FET seems to be prognostic sign of a prosperous outcome after FET.
目的:评价三维功率多普勒超声测量子宫内膜或卵巢参数是否可以预测冷冻胚胎移植(FET)周期的结局。方法:选取30例未见妇科病理(如子宫内膜异位症、子宫肌瘤、任何妇科器官手术)的女性进行FET手术。在首次LH阳性后的自然月经周期3-4天进行FET。在FET当天进行经阴道三维超声检查(Voluson Expert 730, Kretz Zipf, Austria),并在大约一周后预期植入时重复检查。结果测量为子宫内膜形态、厚度、体积、血管化指数(VI)、子宫内膜下体积和VI、优势和非优势卵巢体积和VI。子宫内膜下区域被认为是子宫内膜和子宫肌层之间边界以下5mm。在第二次就诊时,未使用功率多普勒检查子宫内膜。结果:妊娠组(15/30)和非妊娠组(15/30)的人口学、临床和胚胎学特征相似(表)。各组间子宫内膜/子宫内膜下厚度、体积或VI均无差异。子宫内膜三线模式在妊娠组FET当天更为常见(93.3% vs. 40.0%, 95% CI 25.5-81.2%)。FET当天卵巢未见差异(表)。在第二次就诊时,怀孕的患者也更常出现三线模式(91.7%对42.9%,95% CI 18.5-79.1%),但在优势卵巢脉管系统中仍未观察到差异(表)。结论:根据我们的研究结果,在FET当天使用三维超声测量功率多普勒指数并没有为我们提供任何关于周期结果的额外信息。三线模式在FET当天的存在似乎是FET后预后良好的预兆。
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引用次数: 1
P37.08: Twin reversed arterial perfusion (TRAP) sequence: Case report of conservative management and good pregnancy outcome P37.08:双胎动脉灌注逆转(TRAP)序列:保守治疗1例,妊娠结局良好
Pub Date : 2008-08-01 DOI: 10.1002/uog.6062
P. Podobnik, M. Podobnik, J. Zmijanac, B. Gebauer, I. Balenović, I. Brlečić
ultrasound early in gestation. Differential diagnosis is important because of avoiding unnecessary termination. We report here an epigastric heteropagus conjoined female twins case which was characterized by a completely formed fetus with an omphalocele and an adjacent second body consisting with a pelvis and two lower extremities. There was not a bowel or bony connections and there was a thin vascular pedicle between twins. The diagnosis was made with three dimensional ultrasonography at 18 weeks of gestation.
妊娠早期超声检查。鉴别诊断是重要的,因为避免不必要的终止。我们在此报告一例上腹部异腹连体女性双胞胎,其特征是胎儿发育完全,有脐膨出,相邻的第二体包括骨盆和两个下肢。没有肠或骨连接,双胞胎之间有一个薄的血管蒂。在妊娠18周时通过三维超声进行诊断。
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引用次数: 0
OP16.13: Clinical combining‐application of ultrasound and MRI on multiplets malformations OP16.13:超声与MRI在多胞胎畸形中的临床联合应用
Pub Date : 2008-08-01 DOI: 10.1002/uog.5798
A. Xin Lin Chen, B. Yang Xiao Hong, C. Zhu Xia, D. Lu Dan, E. Sun Zi Yan
Objectives: To explore the diagnostic value of antenatal ultrasound combining with in utero magnetic resonance imaging (MRI) in multiplets malformations, and analyze their advantages and limitations. Methods: In the period between 2004 and 2007, 105105 fetuses received ultrasound examination in our hospital. 268 cases were multifetation, including 64 multiplets malformations. And of them 11 multiplets malformations (gestational age ranged from 14–31 weeks), including 8 cases of twin pregnancy and 3 of triplet pregnancy, received MRI examination within 48 hours after ultrasound, all confirmed by autopsy. Retrospectively analyzed, the results of antenatal ultrasound and in utero MRI were compared. Results: In 11 multiplets malformations, there were 6 conjoined twins and 5 acardiac twins with twin-reversed arterial perfusion (TRAP). MRI gave identical diagnostic results with ultrasound, but each had different advantages. (1) MRI was superior to ultrasound in the following aspects: 1. the large view with visualization 2 or 3 fetal organs, even the whole fetus, placenta and amniotic sac simultaneously; 2. visualizing diprosopy of cephalopagus and identifying complex intracranial structures clearly; 3. identifying internal organs of conjoined twins; 4. demonstrating the insertion of umbilical core and the connection with fetus and placenta in acardiac twin.; 5. It showed ‘‘leopard stripe sign’’ in placenta of acardiac twin. (2) Ultrasound was superior to MRI in two aspects: 1. detecting hemodynamic change in TRAP; 2. evaluating cardiac function and finding cardiac anomalies, such as hemicardia of acardiac twin. Conclusions: Ultrasound and MRI are complement with each other in diagnosing multiplets malformations, The combining application of ultrasound and MRI could improve the diagnostic accuracy on multiplets malformations
目的:探讨产前超声联合子宫内磁共振成像(MRI)对多胞胎畸形的诊断价值,并分析其优缺点。方法:2004 ~ 2007年在我院超声检查胎儿105105例。多胎268例,其中畸形多胞胎64例。其中11例多胞胎畸形(胎龄14-31周),其中8例双胎妊娠,3例三胞胎妊娠,均在超声后48小时内行MRI检查,均经尸检证实。回顾性分析,比较产前超声和宫内MRI检查结果。结果:11例畸形多胞胎中,6例为连体双胞胎,5例为双动脉灌注逆转双胞胎。核磁共振成像的诊断结果与超声波相同,但两者都有不同的优势。(1) MRI在以下方面优于超声:大视野,可同时显示2、3个胎儿器官,甚至整个胎儿、胎盘和羊膜囊;2. 头颅畸形的可视化及颅内复杂结构的清晰识别3.鉴定连体双胞胎的内脏器官;4. 心双生子脐心的植入及与胎儿、胎盘的连接5. 双心胎胎盘呈“豹纹征”。(2)超声在两个方面优于MRI:检测TRAP血流动力学变化;2. 评估心脏功能和发现心脏异常,如双心双胞胎的半心绞痛。结论:超声与MRI在诊断多胞胎畸形中是相辅相成的,超声与MRI联合应用可提高多胞胎畸形的诊断准确率
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引用次数: 0
P20.09: Three‐dimensional sonographic assessment of septate uterus before and after hysteroscopic metroplasty P20.09:宫腔镜子宫成形术前后子宫间隔的三维超声评估
Pub Date : 2006-09-01 DOI: 10.1002/uog.3772
E. Vaquero, C. Exacoustos, P. Ligi, E. Valli, N. Lazzarin, M. Romanini, E. Zupi, D. Arduini
as maternal age, ovarian reserve, serum estradiol concentrations, follicular number and size are being investigated as possible prognostic factors of success. In regard to the oocyte quality at the time of retrieval, a relationship between follicular vascularization and the IVF outcome has been established. Conventional pulsatility indices of intra-ovarian arteries are very difficult to use routinely. The aim of this study was to investigate the accuracy of power Doppler ultrasonography for assessment of follicular vascularization during IVF attempts, as well as a prognostic factor of IVF outcome. Methods: 35 patients undergoing IVF treatment were prospectively recruited. Using power Doppler ultrasound, we assessed individual follicular vascularization of about three follicules in each ovary, by a subjective graduation, at the time of oocyte collection. Using a validated system, follicles were determined to be at high or low grade on regard with the extension of vascularization. Subsequent follicular and oocyte quality parameters were collected: mean follicular diameter, presence and maturity of the corresponding oocyte, quality of zygotes and cleaved embryos whether transferred or not. Results: A total of 187 follicles were studied. The assessment of perifollicular vascularization, although highly subjective, was feasible in 92.51% of cases. Vascularization grade was not dependent on follicular size. There was no significant difference in any of the analysed follicular and oocyte quality parameters between high and low grade follicles. Conclusion: Power Doppler assessment of perifollicular vascularization does not seem to be a useful procedure to evaluate follicular and oocyte quality.
随着母亲的年龄,卵巢储备,血清雌二醇浓度,卵泡数量和大小正在研究作为成功的可能的预后因素。关于取卵时的卵母细胞质量,已经建立了卵泡血管化与体外受精结果之间的关系。常规的卵巢内动脉脉搏指数很难常规使用。本研究的目的是探讨功率多普勒超声在体外受精过程中评估卵泡血管形成的准确性,以及体外受精结果的预后因素。方法:前瞻性招募35例接受体外受精治疗的患者。在收集卵母细胞时,我们使用功率多普勒超声评估每个卵巢中约三个卵泡的单个卵泡血管化情况。使用一个经过验证的系统,卵泡被确定为高或低等级与血管化的延伸有关。收集随后的卵泡和卵母细胞质量参数:平均卵泡直径、相应卵母细胞的存在和成熟度、是否移植的受精卵和卵裂胚胎的质量。结果:共研究了187个卵泡。尽管对滤泡周围血管的评价是高度主观的,但92.51%的病例是可行的。血管化分级与卵泡大小无关。在分析的任何卵泡和卵母细胞质量参数在高和低级别卵泡之间没有显著差异。结论:功率多普勒评价滤泡周围血管形成似乎不是一个有用的方法来评估卵泡和卵母细胞的质量。
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引用次数: 0
OP03.18: Brain echogenicities in fetuses at risk for preterm birth OP03.18:有早产风险胎儿的脑回声特征
Pub Date : 2006-09-01 DOI: 10.1002/uog.3125
J. I. D. de Vries, F. R. Rosier-van Dunné, G. van Wezel-Meijler
syndrome). After birth three children showed neurological handicaps in two cases due to postnatally detected syndromes: one Sotos syndrome and one Goldenhar syndrome and one case related to progression of the ventriculomegaly. Conclusions: The outcome of fetuses with isolated mild ventriculomegaly is mostly favorable. Chromosomal anomalies should be excluded in all cases with MVM since in 4.1% of the fetuses trisomy 21 was proven. The risk for a chromosomal anomaly is higher when additional soft markers for aneuploidy are present. Previously published studies on this topic did not take the role of soft markers into consideration. In cases with MVM accompanied by normal karyotype the risk for prenatal and postnatal mortality and morbidity is increased as compared to sonographically normal fetuses.
综合症)。出生后,3名儿童出现神经障碍,其中2例是由于出生后发现的综合征:1例Sotos综合征和1例Goldenhar综合征,1例与脑室肿大进展有关。结论:孤立性轻度脑室肥大胎儿预后良好。在所有MVM病例中应排除染色体异常,因为4.1%的胎儿被证实为21三体。当存在额外的非整倍体软标记时,染色体异常的风险更高。先前发表的关于这一主题的研究没有考虑到软标记物的作用。与超声检查正常的胎儿相比,在核型正常的MVM病例中,产前和产后死亡率和发病率的风险增加。
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引用次数: 0
OC147: Asymptomatic endometrial polyps in postmenopausal women: sonographic surveillance or surgery? OC147:绝经后妇女无症状子宫内膜息肉:超声监测还是手术?
Pub Date : 2004-08-01 DOI: 10.1002/uog.1264
F. Leone, C. Lanzani, T. Bignardi, N. Ciminera, E. Ferrazzi
and relate the results to studies on ultrasound diagnosis in view of necessity of surgical intervention. Material and Methods: Two-hundred and thirty-four ovaries of postmenopausal women, who had died from non-gynaecological diseases, were examined prospectively and consecutively, by the pathologist (G.P. Blom), for cystic structures. The results were compared to recent ultrasound studies of adnexal cysts. Results: Ovarian cysts were found in 15.4% of the women. Paraovarian cysts were found in 4.7% of the women. All cysts were benign, except for one woman, who had bilateral serous cystadenoma of borderline type. Macroscopically the borderline cysts were multilocular with mean diameters of 60 mm and 15 mm, respectively. Conclusions: The results were in agreement with diagnostic ultrasound studies. The fact that we found benign ovarian and paraovarian cysts in 21.1% of the women should in our opinion make the gynecologists reconsider the need for surgical intervention in favor of follow-up.
并结合手术介入的必要性,将结果与超声诊断研究联系起来。材料和方法:由病理学家(gp . p . Blom)对234名死于非妇科疾病的绝经后妇女的卵巢进行前瞻性和连续性检查,以确定是否有囊性结构。结果比较了最近的超声研究附件囊肿。结果:卵巢囊肿发生率为15.4%。在4.7%的女性中发现卵巢旁囊肿。所有的囊肿都是良性的,除了一名妇女,她患有双侧交界型浆液性囊腺瘤。宏观上,交界性囊肿为多房性,平均直径分别为60mm和15mm。结论:结果与诊断性超声检查一致。在21.1%的女性中发现良性卵巢和卵巢旁囊肿,我们认为这应该使妇科医生重新考虑手术干预的必要性,而不是随访。
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引用次数: 0
Fetal ovarian cysts: prenatal diagnosis, management and postnatal outcome 胎儿卵巢囊肿:产前诊断、处理和产后结局
Pub Date : 2002-07-01 DOI: 10.1046/j.1469-0705.2002.00725.x
K. Heling, R. Chaoui, F. Kirchmair, S. Stadie, R. Bollmann
In female fetuses ovarian cysts represent the most important differential diagnosis for intra‐abdominal masses. Analyzing our own patient population we investigated whether there was a connection between sonographic parameters and postnatal course, especially with regard to the need for surgical intervention.
在女性胎儿中,卵巢囊肿是腹内肿块最重要的鉴别诊断。通过分析我们自己的患者群体,我们调查了超声参数与产后病程之间是否存在联系,特别是关于手术干预的需要。
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引用次数: 140
Three‐dimensional obstetric ultrasound (3DUS) is perceived by lay non‐pregnant adults to be more valuable than two‐dimensional ultrasound (2DUS) 产科三维超声(3DUS)被非专业的非怀孕成年人认为比二维超声(2DUS)更有价值。
Pub Date : 2001-10-01 DOI: 10.1046/j.1469-0705.2001.abs20-3.x
A. Hull, D. Pretorius, R. Newton, S. Asfoor, G. James
Purpose:  To determine the impact of 3DUS on non‐pregnant lay adults.
目的:探讨3DUS对未怀孕的非专业成人的影响。
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引用次数: 2
Fetal renal blood flow assessment by three‐dimensional power Doppler ultrasound: preliminary results of a three‐dimensional histogram study 三维功率多普勒超声评估胎儿肾血流:三维直方图研究的初步结果
Pub Date : 2001-10-01 DOI: 10.1046/j.1469-0705.2001.abs28-9.x
F. Chang, C.‐H. Chang, C. Yu, T. Liao, H. Ko
Purpose:  To assess the fetal renal blood flow in normal gestation using three‐dimensional (3D) power Doppler ultrasound.
目的:应用三维功率多普勒超声评价正常妊娠胎儿肾血流量。
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引用次数: 0
Uterine artery Doppler ultrasonography and pregnancy outcome in women with a history of early onset pre‐eclampsia and thrombophilia 子宫动脉多普勒超声检查与早期子痫前期和血栓形成病史妇女妊娠结局的关系
Pub Date : 2001-10-01 DOI: 10.1046/j.1469-0705.2001.abs27-22.x
J. van Eyck, B. Arabin, B. Wibbens
Purpose:  To assess the relationship between persistence after 22 weeks' gestation of the notch in the uterine artery and pregnancy outcome in pregnant women with a history of early onset (<32 weeks) pre‐eclampsia, were tested for thrombophilia and subsequently received medication according to the disorder.
目的:评估早发性(<32周)先兆子痫的孕妇在妊娠22周后子宫动脉缺口的持续存在与妊娠结局的关系,这些孕妇进行了血栓形成检测并随后根据疾病接受了药物治疗。
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引用次数: 0
期刊
Ultrasound in Obstetrics and Gynecology
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