Synthesis of Imidazo[1,2- a ] Pyridine Gem -Amido Vinyl Sulfides, Vinyl Sulfoxides And Vinyl Sulfones. Influence of the Degree of Oxidation of the Sulfur on the Stereoselectivity of the Reaction

S. Céard, M. Vivier, D. Roche, M. Madesclaire
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引用次数: 1

Abstract

( E )-Stereoisomers of imidazo[1,2- a ]pyridine gem -amido vinyl sulfoxides and vinyl sulfones are efficiently prepared by condensation of N , N -diethylphenylsulfinyl or z N , N -diethylphenyl- sulfonylacetamide with imidazo[1,2- a ]pyridine-2-carbaldehyde in the presence of NEt 3 .
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咪唑[1,2- a]吡啶-氨基乙烯基硫化物、乙烯基亚砜和乙烯基砜的合成硫的氧化程度对反应立体选择性的影响
在NEt 3存在下,用N, N -二乙基苯基亚砜或z N, N -二乙基苯基磺酰乙酰胺与咪唑[1,2- a]吡啶-2-乙醛缩合制备了咪唑[1,2- a]吡啶-2-乙醛立体异构体和乙烯基砜。
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