迈向与商业微电极阵列集成的3d打印和自主培养平台

Jesús David Urbano-Gámez, C. Aracil, F. Perdigones, J. A. Fontanilla, José Manuel Quero
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引用次数: 2

摘要

生物学家和医生需要能够研究组织退化的生物学机制的工具,以了解和减缓疾病的影响。通过这种方式,能够将培养维持在适当条件下,甚至长期维持,并与电刺激和采集相兼容的系统,开辟了广阔的应用领域。所提出的设计是一个低成本的便携式系统,可以满足所有这些要求。它基于MEA与电子系统和培养平台的集成,提供了对细胞或组织培养进行电刺激并研究其电活动的可能性。
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Towards a 3D-Printed and Autonomous Culture Platform Integrated with Commercial Microelectrode Arrays
Biologists and physicians need tools that may study the biological mechanisms involved in the degeneration of tissues to understand and slow down the effects of the diseases. In this way, systems able to maintain a culture in its appropriate conditions, even long term, and compatible with electro-stimulation and acquisition, open a wide field of applications. The proposed design is a low-cost portable system that accomplishes all these requirements. It is based on the integration of an MEA with electronic systems, and a culture platform, offering the possibility of electro-stimulation of a cell or tissue culture and studying its electrical activity.
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