{"title":"旋转式生物反应器用于间充质干细胞的生长和分化","authors":"X.S. Teh, Y. Chng, W. Chong, T. Foo","doi":"10.1109/ICBPE.2009.5384090","DOIUrl":null,"url":null,"abstract":"Bone graft generation in vitro is limited by slow nutrient-waste exchange through thick scaffolds and insufficient mechanical stimuli required for induction and differentiation of osteoprogenitor cells, often requiring the use of suitable bioreactors to circumvent these limitations. In this study, we test the suitability of a modified rotary miniPERM™ bioreactor system in inducing proliferation and osteodifferentiation of human foetal mesenchymal stem cell (hfMSC) on poly-ε-caprolactone (PCL)-tricalcium phosphate (TCP) scaffolds.","PeriodicalId":384086,"journal":{"name":"2009 International Conference on Biomedical and Pharmaceutical Engineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Use of a rotary bioreactor for growth and differentiation of mesenchymal stem cells\",\"authors\":\"X.S. Teh, Y. Chng, W. Chong, T. Foo\",\"doi\":\"10.1109/ICBPE.2009.5384090\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Bone graft generation in vitro is limited by slow nutrient-waste exchange through thick scaffolds and insufficient mechanical stimuli required for induction and differentiation of osteoprogenitor cells, often requiring the use of suitable bioreactors to circumvent these limitations. In this study, we test the suitability of a modified rotary miniPERM™ bioreactor system in inducing proliferation and osteodifferentiation of human foetal mesenchymal stem cell (hfMSC) on poly-ε-caprolactone (PCL)-tricalcium phosphate (TCP) scaffolds.\",\"PeriodicalId\":384086,\"journal\":{\"name\":\"2009 International Conference on Biomedical and Pharmaceutical Engineering\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2009 International Conference on Biomedical and Pharmaceutical Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICBPE.2009.5384090\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2009 International Conference on Biomedical and Pharmaceutical Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICBPE.2009.5384090","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Use of a rotary bioreactor for growth and differentiation of mesenchymal stem cells
Bone graft generation in vitro is limited by slow nutrient-waste exchange through thick scaffolds and insufficient mechanical stimuli required for induction and differentiation of osteoprogenitor cells, often requiring the use of suitable bioreactors to circumvent these limitations. In this study, we test the suitability of a modified rotary miniPERM™ bioreactor system in inducing proliferation and osteodifferentiation of human foetal mesenchymal stem cell (hfMSC) on poly-ε-caprolactone (PCL)-tricalcium phosphate (TCP) scaffolds.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
