一种基于静磁耦合的远程查询葡萄糖剂量计

Y. Liu, C. Tong, P. Stoyanov, K. Loiselle, C. Grimes
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摘要

磁性软薄膜元件(见图1)与聚合物层结合,聚合物层会随着葡萄糖浓度的变化而膨胀。剂量计的设计由四个三角形组成,最初间隔50毫米,排列成一个12毫米x 12毫米的正方形,三角形尖端以一个共同原点为中心。随着聚合物尺寸的变化,磁性元件之间的距离也随之变化,因此静磁耦合的磁畴结构也随之变化。所述传感器放置在强度足以切换构成剂量计的集体磁性元件的磁化矢量的可变磁场内。周期性磁化反转产生的磁通量变化可以在适当位置的检测线圈中以一系列电压尖峰的形式检测到。化学分析液的浓度水平可以与时变磁通产生的电压尖峰的振幅有关[1]。图2显示了图1所示的“分裂方形”设计的电压尖峰幅度与元件间距的关系;窗玻璃结构的应用也很成功。传感原理是通用的,并且可以通过适当的聚合物设计来适应传感各种分析物。由于传感器是通过磁通的变化来监测的,因此不需要物理连接来获取传感器信息。
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A remote query glucose dosimeter based -on magnetostatic coupling
Magnetically soft tbin film elements, see Figure 1, are bonded to a polymer layer that is made to swell in response to glucose concentration. The dosimeter design consists of four triangles, initidly spaced 50 )un apart, arranged tn form a 12 mm x 12 mm square with the triangle tips centered at a common origin. As the polymer size changes so does the distance between the magnetic elements and hence tbe magnetic domain structure per magnetostatic coupling. The sensor is placed within a lime varying magnetic field of an intensity sufficient to switch the magnetization vector of the collective magnetic elements comprising the dosimeter. The magnetic flux changes generated by the periodic magnetization reversals can be detected as a series of voltage spikes in suitably lofated detecting coils. Concentration levels of the chemical anal@ can be related to the ampliok of the d e w voltage spike that the time varying flux generates [l]. Figure 2 shows the voltage spike amplitude as afunction of element spacing for tbe 'split square' design shown in Fig. I ; window pane smctures have also been used with success. The sensing principle is general and can be adapted to sense a variety of analytes by appropriate polymer design. Since the sensor is monitored through changes in magneoc flux no physical connections are needed to obtain sensor information.
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