脂族胺类(香叶胺、八角胺、柠檬酸AMP)共感类药物在接受过程中的安全性问题

O. Yakovlev, M. Vakhviyaynen, M. A. Judin, A. Anokhin, A. Konovalov
{"title":"脂族胺类(香叶胺、八角胺、柠檬酸AMP)共感类药物在接受过程中的安全性问题","authors":"O. Yakovlev, M. Vakhviyaynen, M. A. Judin, A. Anokhin, A. Konovalov","doi":"10.47529/2223-2524.2021.4.7","DOIUrl":null,"url":null,"abstract":"Sport nutrition used to reduce weight or improve performance may contain psychostimulant aliphatic amines. The most common of them are DMAA, octodrine and AMP citrate. There are no toxicometric data for above compounds, which prevents their preclinical and clinical study and the formation of optimal dosing regimens or algorithms for overdose therapy. We determined that all of the above drugs have a low degree of cumulation of <20%. Based on the properties of this class of drug, the course should not exceed 7 days in order to avoid complications and the development of addiction.","PeriodicalId":309619,"journal":{"name":"Sports medicine: research and practice","volume":"9 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The problem of the course reception of sympatomimetics from the group of aliphatic amines safety (geranamine, octodrine, AMP citrate)\",\"authors\":\"O. Yakovlev, M. Vakhviyaynen, M. A. Judin, A. Anokhin, A. Konovalov\",\"doi\":\"10.47529/2223-2524.2021.4.7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Sport nutrition used to reduce weight or improve performance may contain psychostimulant aliphatic amines. The most common of them are DMAA, octodrine and AMP citrate. There are no toxicometric data for above compounds, which prevents their preclinical and clinical study and the formation of optimal dosing regimens or algorithms for overdose therapy. We determined that all of the above drugs have a low degree of cumulation of <20%. Based on the properties of this class of drug, the course should not exceed 7 days in order to avoid complications and the development of addiction.\",\"PeriodicalId\":309619,\"journal\":{\"name\":\"Sports medicine: research and practice\",\"volume\":\"9 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-05-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sports medicine: research and practice\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47529/2223-2524.2021.4.7\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sports medicine: research and practice","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47529/2223-2524.2021.4.7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

用于减肥或提高成绩的运动营养可能含有精神兴奋剂脂肪胺。其中最常见的是DMAA,八磷酸腺苷和柠檬酸腺苷。上述化合物没有毒理学数据,这阻碍了它们的临床前和临床研究,也阻碍了过量治疗的最佳给药方案或算法的形成。我们确定上述药物均具有<20%的低累积度。根据这类药物的性质,疗程不应超过7天,以避免并发症和成瘾的发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The problem of the course reception of sympatomimetics from the group of aliphatic amines safety (geranamine, octodrine, AMP citrate)
Sport nutrition used to reduce weight or improve performance may contain psychostimulant aliphatic amines. The most common of them are DMAA, octodrine and AMP citrate. There are no toxicometric data for above compounds, which prevents their preclinical and clinical study and the formation of optimal dosing regimens or algorithms for overdose therapy. We determined that all of the above drugs have a low degree of cumulation of <20%. Based on the properties of this class of drug, the course should not exceed 7 days in order to avoid complications and the development of addiction.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
0.30
自引率
0.00%
发文量
0
期刊最新文献
Response of cardiorespiratory system during maximal exercise cycle ergometer test in women cross-country skiers with different skills levels Practical recommendations for safe reduction of body weight in combat sports: scoping review Jump-to-Box exercise has an increasing effect on jumping ability in adolescents Changes in the oxidative-antioxidant status of blood in freestyle wrestlers under the influence of physical exertion The effect of voluntary hypoventilation in yoga breathing exercises on gas exchange and EEG activity in healthy trained subjects
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1