D B Korman, S L Potapov, V I Shamaev, N P Pal'mina, E B Burlakova
{"title":"[化疗对弥散性乳腺癌患者血浆磷脂和红细胞总不饱和度及组成的影响]。","authors":"D B Korman, S L Potapov, V I Shamaev, N P Pal'mina, E B Burlakova","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The total unsaturation and composition of blood phospholipids were studied in patients with disseminated breast cancer prior to and after chemotherapy. It was shown that the level of double bonds in blood lipids was quite definitely related to the effect of treatment and may have an independent prognostic significance. A correlation was established between the survival of patients and the character of changes in the level of double bonds after chemotherapy. The treatment did not influence the relative content of different fractions and the oxidizability of plasma phospholipids and erythrocytes.</p>","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1992-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The effect of chemotherapy on the total unsaturation and composition of plasma phospholipids and erythrocytes in patients with disseminated breast cancer].\",\"authors\":\"D B Korman, S L Potapov, V I Shamaev, N P Pal'mina, E B Burlakova\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The total unsaturation and composition of blood phospholipids were studied in patients with disseminated breast cancer prior to and after chemotherapy. It was shown that the level of double bonds in blood lipids was quite definitely related to the effect of treatment and may have an independent prognostic significance. A correlation was established between the survival of patients and the character of changes in the level of double bonds after chemotherapy. The treatment did not influence the relative content of different fractions and the oxidizability of plasma phospholipids and erythrocytes.</p>\",\"PeriodicalId\":14529,\"journal\":{\"name\":\"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1992-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[The effect of chemotherapy on the total unsaturation and composition of plasma phospholipids and erythrocytes in patients with disseminated breast cancer].
The total unsaturation and composition of blood phospholipids were studied in patients with disseminated breast cancer prior to and after chemotherapy. It was shown that the level of double bonds in blood lipids was quite definitely related to the effect of treatment and may have an independent prognostic significance. A correlation was established between the survival of patients and the character of changes in the level of double bonds after chemotherapy. The treatment did not influence the relative content of different fractions and the oxidizability of plasma phospholipids and erythrocytes.