[化疗对弥散性乳腺癌患者血浆磷脂和红细胞总不饱和度及组成的影响]。

D B Korman, S L Potapov, V I Shamaev, N P Pal'mina, E B Burlakova
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引用次数: 0

摘要

研究了弥散性乳腺癌患者化疗前后血磷脂总不饱和度及组成。结果表明,血脂双键水平与治疗效果有相当明确的关系,并可能具有独立的预后意义。在化疗后双键水平的变化特征与患者的生存之间建立了相关性。不同组分的相对含量及血浆磷脂和红细胞的氧化性均未受影响。
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[The effect of chemotherapy on the total unsaturation and composition of plasma phospholipids and erythrocytes in patients with disseminated breast cancer].

The total unsaturation and composition of blood phospholipids were studied in patients with disseminated breast cancer prior to and after chemotherapy. It was shown that the level of double bonds in blood lipids was quite definitely related to the effect of treatment and may have an independent prognostic significance. A correlation was established between the survival of patients and the character of changes in the level of double bonds after chemotherapy. The treatment did not influence the relative content of different fractions and the oxidizability of plasma phospholipids and erythrocytes.

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