Beate Ørbeck, Hans Jørgen Berntsen, Kristin Romvig Øvergaard
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背景:挪威社会沟通问卷(SCQ)在儿童精神病学中识别自闭症谱系障碍(ASD)的准确性尚不清楚。方法:探讨SCQ在鉴别临床诊断的ASD以及发育、维度和诊断性访谈(3Di)和自闭症诊断观察量表(ADOS-2)分类的ASD中的准确性。结果:SCQ cut-off为15时,临床诊断ASD的正确分类敏感性(Se)较低(Se = 38%),而ADOS-2分类ASD的特异性(Se = 30%)分别为78%和76%。对于3Di分类的ASD, Se略高(49%),特异性较好(86%),阳性预测值最高(0.73)。结论/意义:SCQ在儿童精神病学中识别临床ASD诊断的准确性较低。然而,SCQ得分达到或高于阈值的儿童也有很高的风险根据3Di被归类为ASD。我们建议未来的研究包括更多关于最终诊断结论基础的详细信息。此外,SCQ的特征应该在广泛的ASD范围内的儿童样本中进行评估,包括发育迟缓的个体。还需要调查其他筛查工具在儿童精神病诊所诊断工作中的适用性。关键词:自闭症诊断观察表(ADOS-2),发育维度与诊断访谈(3Di),敏感性;社会沟通问卷(SCQ)
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Hvor nøyaktig identifiserer screeninginstrumentet Social Communication Questionnaire autismespekterforstyrrelser i BUP?
Background: The accuracy of the Norwegian Social Communication Questionnaire (SCQ) in identifying autism spectrum disorder (ASD) within child psychiatry is not known. Method: We investigated the accuracy of SCQ in identifying clinically diagnosed ASD and ASD classified by the Developmental, Dimensional and Diagnostic Interview (3Di) and the Autism Diagnostic Observation Schedule (ADOS-2). Results: The SCQ cut-off of 15 showed low sensitivity (Se) for correct classification of clinically diagnosed ASD (Se = 38%) and ADOS-2 classified ASD (Se = 30%) with 78% and 76% specificity (SP), respectively. For 3Di classified ASD, Se was somewhat higher (49%) and had good specificity (86%), with the best positive predictive value (.73). Conclusions/Implications: The SCQ showed low accuracy in identifying a clinical ASD diagnosis in child psychiatry. However, children with SCQ scores at or above threshold had a high risk of also being categorised with ASD according to the 3Di. We recommend that future studies include more detailed information about the basis for the final diagnostic conclusions. Furthermore, SCQ's characteristics should be evaluated in samples of children within a broad range of ASD that includes individuals with delayed development. Investigation of the suitability of other screening instruments for ASD for diagnostic work in child psychiatric clinics is also needed. Keywords: Autism Diagnostic Observation Schedule (ADOS-2), Developmental, Dimensional and Diagnostic Interview (3Di), sensitivity; specificity, Social Communication Questionnaire (SCQ)
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