M M Rasulov, I G Kuznetsov, L K Bartkova, S K Suslova, A A Belousov, M G Voronkov
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[An analysis of the possible mechanism of the ulcerostatic action of 1-ethoxysilatrane].
Stimulating effect of 1-ethoxysilatrane on healing processes of experimental stomach ulcers was studied in rats. 1-ethoxysilatrane inhibited lipid peroxidation in blood and stomach wall tissues, interacted with artificial membranes, and affected the rate of mitochondrial respiration in liver. A hypothesis is put forward on the membranotropic effect of 1-ethoxysilatrane which underlies its ulcerostatic effect.
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