B A Kudriashov, L A Liapina, V E Pastorova, M V Kondashevskaia
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[The blood anticoagulant system in rats perorally administered a heparin-acetylsalicylic acid complex].
Heparin/acetylsalicylate complexes (1:9 and 10:1) were obtained in vitro. Single or chronic (7-8 days) per os administration to white rats of 0.1% solution of the heparin/acetylsalicylate complex (0.3 ml/200 g body weight) enhanced anticoagulative properties of blood plasma, increased the fibrinolytic activity in respect of stabilized fibrin, and diminished the thrombin-induced platelet aggregation.
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