都是新生儿的肺超音波训练出的问题

D. Brandt
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摘要

背景:呼吸窘迫(RD)是最常见的新生儿疾病。肺超声(LUS)是一种以前在新生儿RD研究中测试过的技术,但关于其常规临床适用性的文献仍然缺乏。目的:评价不同培训水平的新生儿医师所做的LUS与新生儿出生后24 h胸部x线检查诊断RD的一致性。方法:我们招募了出生后24小时内患有RD的新生儿。患者行LUS和CXR。比较LUS和CXR诊断的一致性。20%的患者接受了两个LUS(一个来自经验丰富的超声医师,一个来自新手超声医师)来计算观察者间的一致性。测量了LUS和CXR以及新手和专家操作人员达到诊断所需的时间差异。结果:我们研究了124例患者;报告134例诊断。LUS与CXR诊断的一致性为91% (95% CI 86 ~ 96%), κ统计量为0.88 (95% CI 0.81 ~ 0.94)。LUS的中位诊断时间(9.5 min, IQR 5-15)短于CXR (50 min, IQR 33-64) (p < 0.0001)。在25/124例患者中,LUS由新手和经验丰富的超声医师进行,完全一致。专家的中位诊断时间(9 min, IQR 5-15)短于新手(15 min, IQR 10-20) (p < 0.0002)。结论:LUS与CXR在新生儿RD的鉴别诊断中具有较高的一致性。LUS的手术时间比CXR短。
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Alles eine Frage des Trainings - Lungenultraschall bei Neugeborenen
Background: Respiratory distress (RD) is the most common neonatal illness. Lung ultrasound (LUS) is a technique previously tested in neonatal studies on RD, but literature regarding its routine clinical applicability is still lacking. Objective: To assess the concordance between LUS performed by neonatologists with different training levels and chest X-ray (CXR) for the diagnosis of RD in newborns during the first 24 h of life. Methods: We enrolled newborns with RD during the first 24 h of life. Patients under went LUS and CXR. LUS and CXR diagnosis were compared to evaluate concordance. Twenty percent of patients received two LUS (one from an experienced and one from a novice sonographer) to calculate the interobserver agreement. The difference in time needed to reach a diagnosis with LUS and CXR, and from novice and expert operators, was measured. Results: We studied 124 patients; 134 diagnoses were reported. The concordance between LUS and CXR diagnosis was 91% (95% CI 86-96%) with a κ statistic of 0.88 (95% CI 0.81-0.94). The median time to diagnosis was shorter for LUS (9.5 min, IQR 5-15) than for CXR (50 min, IQR 33-64) (p < 0.0001). In 25/124 patients, LUS was performed by both novice and experienced sonographers with complete concordance. The median time to diagnosis was shorter for expert (9 min, IQR 5-15) than novice operators (15 min, IQR 10-20) (p < 0.0002). Conclusion: LUS and CXR have a high concordance in the differential diagnosis of neonatal RD in the first 24 h of life. LUS has a shorter operation time than CXR.
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