纳米草坪表面的细胞粘附

Chang‐Hwan Choi, S. Hagvall, J. Dunn, B. Wu, C. Kim
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引用次数: 0

摘要

我们报告了纤维持久体在密集的尖端纳米柱结构上的细胞粘附的各个方面,我们称之为“纳米草皮”。控制纳米结构的大小、形状和纵横比的能力使研究细胞-基质粘附的表面三维效应成为可能。据我们所知,这是第一次系统地研究纳米三维表面形貌对细胞粘附的影响。
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Cell Adhesions on Nanoturf Surfaces
We report on various aspects of cell adhesion of fibrolasts over densely-populated sharp-tip nano-post structures, which we term “ NanoTurf”. The ability to control the size, shape, and aspect ratio of the nanostructures enabled the study on the effect of surface three-dimensionality of the cell-matrix adhesion in detail. To our best knowledge, this is the first systematic investigation of the nanometric three-dimensional surface topography effect on cell adhesions.
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