8-芳基-7-en-2,4,6-三酮作为区域选择性合成一些新的2-甲基-5-苯基-7-硫氧基-6,7-二氢吡唑[1,5-c]嘧啶的有用前体

IF 0.2 4区 化学 Q4 CHEMISTRY, ORGANIC Indian Journal of Heterocyclic Chemistry Pub Date : 2023-09-30 DOI:10.59467/ijhc.2023.33.355
Nisha Sharma, Rashmi Pundeer, Om Prakash
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引用次数: 0

摘要

脱氢乙酸,通常缩写为DHA,其衍生物作为重要的中间体被广泛应用于有机合成,特别是杂环化合物的合成。8-芳基-7-烯-2,4,6-三酮(DHA-三酮,可由市售的DHA通过多步骤制备)与硫代氨基脲反应生成了一些新的2-甲基-5-苯基-7-硫氧基-6,7-二氢吡唑[1,5-c]嘧啶。
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8-Aryloct-7-en-2,4,6-triones as Useful Precursors for the Regioselective Synthesis of Some New 2-Methyl-5-styryl-7-thioxo-6,7-dihydropyrazolo[1,5-c]pyrimidines
Dehydroacetic acid, commonly abbreviated as DHA, and its derivatives have been extensively used as important intermediates in organic synthesis particularly for the synthesis of heterocyclic compounds. The reaction of 8-aryloct-7-en-2,4,6-triones (DHA-triones, readily prepared from commercially available DHA by the use of a multistep procedure) with thiosemicarbazide led the formation of some new 2-methyl-5-styryl-7-thioxo-6,7-dihydropyrazolo[1,5-c] pyrimidines.
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来源期刊
CiteScore
0.40
自引率
33.30%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Indian Journal of Heterocyclic Chemistry is exclusively devoted to research in the area of heterocyclic chemistry. The journal publishes invited review articles and original research papers pertaining to structure and synthesis, mechanism of reactions, spectral studies, biologically active compounds, bio-chemical studies, physicochemical work, phytochemistry etc.
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