软化学技术合成的掺铁氧化镁纳米粒子的电传输和抗菌特性

Joyshree Maji , Sanjeev Pandey , Soumen Basu
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引用次数: 0

摘要

采用一种简单的软化学方法合成了Fe掺杂MgO纳米颗粒。我们对晶粒尺寸范围为7-10 nm的fe掺杂MgO纳米颗粒的电学性能进行了全面的测试。同时,我们探索了它们的抗菌能力。我们的研究结果表明,铁掺杂MgO浓度的增加与增强的杀菌效果相关。为了更深入地了解电荷转移过程,研究了样品在不同温度和频率下的交流电导率和介电特性。除电特性外,还利用MIC方法,活计数(LC)方法和琼脂杯技术研究了抗菌活性。暴露于纳米颗粒后,我们通过透射电子显微镜(TEM)分析观察到致病细胞壁的破坏。这些结果表明,铁掺杂的MgO纳米颗粒有望开发出新的、更有效的抗菌药物。fe掺杂MgO纳米粒子对大肠杆菌和芽孢杆菌的MIC值分别为2.75 μg/ml和1.75 μg/ml。这一剂量水平可能在医学领域得到应用。然而,需要进一步调查以评估潜在的毒性以及对环境和人类健康的长期影响。如果体内试验成功,掺铁氧化镁纳米颗粒可能成为有价值的抗菌剂。
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The electrical transport and antibacterial properties of Fe doped MgO nanoparticles synthesized by a soft chemical technique

Fe doped MgO nanoparticles were synthesized using a straightforward soft chemical method. We conducted a comprehensive examination of the electrical properties of Fe-doped MgO nanoparticles with a crystalline size range of 7–10 nm. Simultaneously, we explored their antibacterial capabilities. Our findings indicate that an increase in the concentration of Fe-doped MgO correlates with an enhanced bactericidal effect. To gain a deeper understanding of charge transfer processes, the AC conductivity and dielectric characteristics of the samples across various temperatures and frequencies was studied.The antibacterial activity was studied utilising the MIC methodology, the live count (LC) method, and the agar cup technique in addition to the electrical characteristics. After exposure to nanoparticles, we observed the disruption of pathogenic cell walls through transmission electron microscopy (TEM) analysis. These results suggest that Fe-doped MgO nanoparticles hold promise for the development of novel, more effective antibacterial drugs. The ½ MIC for E.coli was found to be 2.75 μg/ml, while for Bacillus sp., it was 1.75 μg/ml when exposed to Fe-doped MgO nanoparticles. This dosage level may find applications in the medical field. However, further investigations are required to assess potential toxicity and long-term environmental and human health effects. If successful in vivo tests follow, Fe-doped MgO nanoparticles could emerge as valuable antibacterial agents.

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