帕金森病的病理生理学和替代疗法综述

M. Gangaraju, P. Sravya, N. V. L. Suvarchala Reddy V, K. V. Srinija, K. Keerthana
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摘要

神经系统疾病是指大脑或周围神经中的神经元在死亡前逐渐失去活动能力。不幸的是,目前还没有治疗退行性疾病的方法,只能阻止疾病的发展。实际上,目前有几种对症治疗方法,但退行性疾病仍然无法治愈。西医疗法有一定的优势,如深部脑刺激疗法、帕金森病和运动障碍的多巴胺分泌疗法、治疗记忆问题的胆碱酯酶抑制剂、对抗阿尔茨海默病行为和精神表现的抗精神病药物、治疗炎症的镇痛药物、治疗传导的抗炎药物,以及可能用于治疗严重和加剧症状的治疗记忆障碍的抗精神病药物。此外,科学家们还试图发现可能延缓疾病发作的治疗方法,其中包括治疗痴呆症的镇痛药(非甾体类消炎药)、治疗致命运动神经元疾病的利鲁唑、震颤和亨廷顿舞蹈症。虽然专门的药物可以帮助缓解一些症状。然而,它们仍然存在许多问题。年龄会大大增加个人患上影响大脑的疾病的风险。在未来几十年中,神经退行性疾病可能会增加。为了更好地了解脑部疾病背后的机制,我们必须想出新颖的治疗和预防方法。因此,我们开始寻找更多治疗这些疾病的方法,并找到了一些选择。例如植物药、物理疗法、干细胞疗法、单克隆抗生素。
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A Comprehensive Review on Pathophysiology and Alternative Therapies for Parkinsons Disease
A neurological disorder is one in which neurons in the cerebral or peripheral nerves gradually lose their ability to operate before dying. Unfortunately, there is presently no treatment for degenerative diseases, only an arrest down of the disease's progression. There are actually several symptomatic treatments available, however degenerative conditions are still incurable. There are certain advantages with western medical treatments, they are Deep brain stimulation, dopamine-producing treatments for Parkinson's disease (PD) and disorders of movement, cholinesterase inhibition for memory problems, antipsychotic medicines to combat the behavioural and mental manifestations of Alzheimer's disease, analgesic medicines for Inflammation, anti-inflammatory agents for transmission, and possibly antipsychotic drugs medications for memory impairment may be used to treat the severe and raising symptoms. Additionally, scientists have sought to discover treatments that might delay the onset of disorders, which include Analgesics (non-steroidal anti-inflammatory in nature drugs) treating dementia, Riluzole treatment fatal motor neuron disease, tremors, and Huntington's chorea. Although specialized medications may assist relieve a few of the signs. There nevertheless remain so many problems with them. Age significantly increases the individual's risk of having a condition that affects the brain. In the future decades, there may be an increase in neurodegenerative illnesses. To better understand the mechanisms behind diseases of the brain, we must come up with novel approaches to both therapy and prevention. Thus we started searching for more treatments for these diseases as a result of this, and we found some options. Such as plant medicine, physiotherapy, stem cell therapy, monoclonal antibiotics.
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