基于磁性纳米粒子 (MNPs) 系统的功能化和潜在应用范围综述

Sunny Sharma , Harsha Sharma , Renu Sharma
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摘要

近年来,磁性纳米粒子(MNPs)因其广泛的应用范围而越来越受欢迎。本综述文章为年轻科学家提供了一站式参考,因为它涵盖了有关基于 MNPs 系统的合成和功能化方法及其在不同领域的潜在应用范围的文献报道。这篇综述详细总结了文献中报道的合成 MNPs 的不同方法、MNPs 功能化的必要性、活性物种在功能化 MNPs 表面的固定化及其在进行重要的生物有机转化中的应用。MNPs 的应用不仅限于催化领域,而且在不同行业也有潜在应用。在过去几十年里,由于有害染料和有毒金属对水体的污染,全球对公共卫生问题的关注与日俱增。监测并随后清除受污染水体中的这些有害染料和有毒金属是当今环境修复的主要关注点之一。在这种情况下,基于 MNPs 的吸附剂因其去除效率高、成本低、动力学速度快、易于获得和设计灵活等优点,在去除水体中的有害污染物方面显示出了巨大的潜力。此外,MNPs 还证明了其在酶和制药领域的潜力。MNPs 作为一类主要的纳米级材料,正在彻底改变当前的临床诊断和治疗技术,目前正被用作下一代药物载体。此外,基于磁性纳米粒子的生物传感器还被用于检测 SARS-CoV-2 的存在,这是一种核糖核酸(RNA)病毒,在 COVID-19 大流行中造成了近 610 万人死亡。基于 MNPs 的系统还显示了其在燃料工业中的潜力,因为它可用于生产生物柴油,而生物柴油因其环保、清洁和可生物降解的特性,成为化石燃料能源的一种有前途的替代能源。总之,我们深入详细地介绍了 MNPs、其合成、功能化及其在不同领域的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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A review on functionalization and potential application spectrum of magnetic nanoparticles (MNPs) based systems

Magnetic nanoparticles (MNPs) owing to its broad application spectrum are gaining popularity in recent years. The current review article offers a one-stop-reference for young scientists as it encompasses the literature reports on method of synthesis and functionalization of MNPs based systems and their potential applications spectrum in diverse fields. This review summarizes in details about different methods reported in literature for the synthesis of MNPs, need of functionalization of MNPs, immobilization of active species onto the surface of functionalized MNPs and their applications in carrying out biologically important organic transformation. Applications of MNPs are not only restricted to the field of catalysis but also showed potential applications in different sectors. Over the last few decades, there has been increasing global concern over public health issues due to contamination of water bodies with harmful dyes and toxic metals. Monitoring and subsequent removal of these harmful dyes and toxic metals from the contaminated water is one of the major environmental remediation interests today. In this context, MNPs based absorbents have shown exuberant potential to remove deleterious pollutants from water bodies owing to their high removal efficiency, low cost, faster kinetics, easy accessibility and design flexibility. Besides, MNPs have also proved their potential in the field of enzyme and pharmaceutical industries. MNPs being the major class of nanoscale materials are revolutionizing the current clinical diagnostic and therapeutic techniques and are currently employed as next generation drug carriers. Furthermore, Magnetic NP-Based Biosensors was also employed for detection of the presence of SARS-CoV-2, a ribonucleic acid (RNA) virus responsible for nearly 6.1 million deaths occurred due to COVID-19 pandemic. MNPs based system also showed their potential in fuel industry as it is used in the production of biodiesel which emerges as a promising alternative to fossil fuel derived energy sources because it is eco-friendly, clean and biodegradable in nature. In short, we have provided in-depth details about the MNPs, their synthesis, functionalization and their applications in diverse fields.

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