Correlations between Optical Coherence Tomography Angiography Parameters and the Visual Acuity in Patients with Central Retinal Vein Occlusion

Background: Central retinal vein occlusion (CRVO) is the second most common retinal vascular disorder next to diabetic retinopathy. This study aimed to study the optical coherence tomography angiography (OCTA) findings in patients with central retinal vein occlusion (CRVO) and their relationship to the best correct visual acuity (BCVA) at presentation. Subject and Methods: A total of 40 cases with CRVO were evaluated. Patients were grouped into 2 groups according to BCVA at presentation, group I with BCVA ≤ of 1.0 logMAR and group II with BCVA > 1.0 logMAR. OCTA studies were performed after resolution of the cystoid macular edema (CME) following a serial of intravitreal anti vascular endothelial growth factors (VEGF) injections to ensure reliability of the data. OCTA findings were recorded and correlated to BCVA. Result: Regarding FAZ diameter it was significantly larger in cases with BCVA > 1.0 LogMAR (0.71) than study group with BCVA ≤ 1.0 LogMAR (0.39) (P<0.001). Regarding SVD, SFVD, SPFVD, DVD, DFVD, DPFVD, it was significantly lower in study group with BCVA > 1.0 than study group with BCVA ≤ 1.0. Conclusion: OCTA is a fast, noninvasive, and effective examination for CRVO that can display the vascular density and the FAZ area quantitatively and distinctly. An enlarged FAZ area and disruption of the foveal avascular zone correlated significantly with poorer visual outcomes.