关于丙酮酸补充剂的现有知识:简要回顾

IF 2.3 Q2 SPORT SCIENCES Sports Medicine and Health Science Pub Date : 2024-02-28 DOI:10.1016/j.smhs.2024.02.007
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引用次数: 0

摘要

丙酮酸是一种三碳酮酸,天然存在于细胞中。它通过糖酵解途径中的酶促反应产生,在能量代谢中起着至关重要的作用。尽管早期的研究结果令人鼓舞,但后来对体力活动量大的人进行的良好对照研究表明,补充丙酮酸的时间超过 1 周,就不会产生增强体力的效果。不过,一些数据表明,摄入的丙酮酸可能会被优先代谢,而不会在血液中蓄积。丙酮酸具有抗氧化活性,可影响细胞的氧化还原状态,外源性丙酮酸可通过影响血液的酸碱平衡来影响新陈代谢。这篇简短的综述将重点讨论丙酮酸盐作为补充剂对活跃人群的潜在影响。目前的认识表明,对丙酮酸补充剂影响的研究应优先调查丙酮酸摄入的时间。
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Current knowledge about pyruvate supplementation: A brief review

Pyruvate is a three-carbon ketoacid that occurs naturally in cells. It is produced through enzymatic reactions in the glycolytic pathway and plays a crucial role in energy metabolism. Despite promising early results, later well-controlled studies of physically active people have shown that pyruvate supplementation lasting more than 1 week has no ergogenic effects. However, some data suggest that ingested pyruvate may be preferentially metabolized without accumulation in the bloodstream. Pyruvate exhibits antioxidant activity and can affect the cellular redox state, and exogenous pyruvate can influence metabolism by affecting the acid-base balance of the blood. This brief review focuses on the potential effects of pyruvate as a supplement for active people. The current state of understanding suggests that studies of the effects of pyruvate supplementation should prioritize investigating the timing of pyruvate intake.

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来源期刊
Sports Medicine and Health Science
Sports Medicine and Health Science Health Professions-Physical Therapy, Sports Therapy and Rehabilitation
CiteScore
5.50
自引率
0.00%
发文量
36
审稿时长
55 days
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