基于核心模式的新型蝶形非对称开槽传感器,用于蔗糖浓度的超高灵敏度检测

IF 10.61 Q3 Biochemistry, Genetics and Molecular Biology Biosensors and Bioelectronics: X Pub Date : 2024-05-08 DOI:10.1016/j.biosx.2024.100486
Md.Sen Bin Mustafiz, Md.Arafat Rahman, Nafisa Tasnim, Tanvir Ahmed
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引用次数: 0

摘要

在这项研究中,我们提出了一种使用光子晶体光纤(PCF)的非对称矩形开槽生物传感器,它受表面等离子体共振(SPR)的影响。该传感器只使用了七个气孔,确保了更好的制造可行性,其特性是通过基于有限元法(FEM)的数值分析确定的。为了简化制造工艺并确保化学稳定性,在结构的周边采用了化学不渗透的金(Au)条作为等离子材料。在有效的结构参数下,该传感器的最大振幅灵敏度为 663.13 RIU-1,最大波长灵敏度为 204,000 nm/RIU,Y 极化模式的最大波长分辨率为 4.90 × 10-7 RIU。它的线性度也高达 0.9849。在检测蔗糖含量时,它的最大波长灵敏度为 207070.71 nm/RIU,最大振幅灵敏度为 662.80 RIU-1。新推出的传感器可在 1.28 至 1.41 的宽光谱范围内检测各种分析物的折射率 (RI)。这一广泛的检测范围使传感器能够精确测量高达 40% 的蔗糖浓度。这一宽广的检测范围可用于分析蔗糖、病毒、癌细胞、蛋白质等各种分析物。
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A novel butterfly-shaped core mode-based asymmetric slotted sensor for ultra-high sensitivity in sucrose concentration detection

In this research, we proposed an asymmetric rectangular slotted biosensor using photonic crystal fiber (PCF), which is subject to surface plasmon resonance (SPR). The proposed sensor utilizes only seven air holes, ensuring better fabrication feasibility and their properties are determined through finite element method (FEM)-based numerical analysis. To simplify the manufacturing process and ensure chemical stability, chemically impermeable gold (Au) strips are employed around the perimeter of the structure as the plasmonic material. With effective structural parameters, the maximum amplitude sensitivity for the proposed sensor is 663.13 RIU1, the maximum wavelength sensitivity is 204,000 nm/RIU, and the maximum wavelength resolution is 4.90 × 10−7 RIU for the y-polarized mode. It also shows a high linearity of 0.9849. For the detection of sucrose content, it has a maximum wavelength sensitivity of 207070.71 nm/RIU and a maximum amplitude sensitivity of 662.80 RIU1. The newly introduced sensor can detect the refractive index (RI) of various analytes across a broad spectrum, ranging from 1.28 to 1.41. This extensive detection range allows the sensor to precisely measure sucrose concentrations up to 40%. This broad range enables the analysis of various analytes like sucrose, viruses, cancer cells, proteins, and numerous others.

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来源期刊
Biosensors and Bioelectronics: X
Biosensors and Bioelectronics: X Biochemistry, Genetics and Molecular Biology-Biophysics
CiteScore
4.60
自引率
0.00%
发文量
166
审稿时长
54 days
期刊介绍: Biosensors and Bioelectronics: X, an open-access companion journal of Biosensors and Bioelectronics, boasts a 2020 Impact Factor of 10.61 (Journal Citation Reports, Clarivate Analytics 2021). Offering authors the opportunity to share their innovative work freely and globally, Biosensors and Bioelectronics: X aims to be a timely and permanent source of information. The journal publishes original research papers, review articles, communications, editorial highlights, perspectives, opinions, and commentaries at the intersection of technological advancements and high-impact applications. Manuscripts submitted to Biosensors and Bioelectronics: X are assessed based on originality and innovation in technology development or applications, aligning with the journal's goal to cater to a broad audience interested in this dynamic field.
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