一些杂环化合物的新合成及其对破坏性陆地蜗牛 Theba pisana 的杀软体动物活性

IF 5.2 2区 农林科学 Q1 AGRICULTURE, MULTIDISCIPLINARY Chemical and Biological Technologies in Agriculture Pub Date : 2024-06-12 DOI:10.1186/s40538-024-00602-z
Ahmed Abdou O. Abeed, Talaat I. El-Emary, Mohamed Salah K. Youssef, Ibrahim Hefzy, Hesham A. M. Ibrahim
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引用次数: 0

摘要

背景在地中海地区,尤其是在埃及,陆生蜗牛,特别是 Theba pisana,是重要的农业害虫。它们是腹足纲动物,会对各种植被造成严重破坏,是造成经济损失的重要农业害虫。为此,我们开发了独特的无毒软体杀虫剂。这项研究评估了九种新型杂环化合物,并将灭多威作为参考化合物,以研究它们对 T. pisana 的杀软体动物作用。这些杂环包括 2-吡唑啉类、2-氧代环己-3-烯和 3-氰基-2-乙氧基吡啶。甲氧苄啶的毒性最高,其次是丙-2-烯-1-酮和 1-硫代氨基甲酰-2-吡唑啉衍生物,半数致死浓度分别为 44.14、59.54 和 72.00 ppm。
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Novel synthesis of some heterocycles and their molluscicidal activity against the destructive land snail, Theba pisana

Background

Terrestrial snails, specifically Theba pisana, represent significant agricultural pests in the Mediterranean region, particularly in Egypt. They are gastropods that cause substantial damage to a variety of vegetation, rendering them important agricultural pests that result in economic losses. In response, we have developed unique and non-toxic molluscicides. The study assessed nine novel heterocycles compared with methomyl as a reference compound, to study their molluscicidal effects on T. pisana. These heterocycles include 2-pyrazolines, 2-oxocyclohex-3-ene, and 3-cyano-2-ethoxypyridine.

Results

The obtained data revealed that the majority of the produced chemicals were remarkably effective against T. pisana snails, exhibiting different degrees of toxicity seven days post-treatment. Methomyl exhibited the highest toxicity, followed by prop-2-en-1-one and 1-thiocarbamoyl-2-pyrazoline derivatives, with LC50 values of 44.14, 59.54, and 72.00 ppm, respectively.

Conclusions

These findings will inform the potential of these synthetic compounds as one of the sources for molluscicide development and their integration into pest management strategies.

Graphical Abstract

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来源期刊
Chemical and Biological Technologies in Agriculture
Chemical and Biological Technologies in Agriculture Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
6.80
自引率
3.00%
发文量
83
审稿时长
15 weeks
期刊介绍: Chemical and Biological Technologies in Agriculture is an international, interdisciplinary, peer-reviewed forum for the advancement and application to all fields of agriculture of modern chemical, biochemical and molecular technologies. The scope of this journal includes chemical and biochemical processes aimed to increase sustainable agricultural and food production, the evaluation of quality and origin of raw primary products and their transformation into foods and chemicals, as well as environmental monitoring and remediation. Of special interest are the effects of chemical and biochemical technologies, also at the nano and supramolecular scale, on the relationships between soil, plants, microorganisms and their environment, with the help of modern bioinformatics. Another special focus is the use of modern bioorganic and biological chemistry to develop new technologies for plant nutrition and bio-stimulation, advancement of biorefineries from biomasses, safe and traceable food products, carbon storage in soil and plants and restoration of contaminated soils to agriculture. This journal presents the first opportunity to bring together researchers from a wide number of disciplines within the agricultural chemical and biological sciences, from both industry and academia. The principle aim of Chemical and Biological Technologies in Agriculture is to allow the exchange of the most advanced chemical and biochemical knowledge to develop technologies which address one of the most pressing challenges of our times - sustaining a growing world population. Chemical and Biological Technologies in Agriculture publishes original research articles, short letters and invited reviews. Articles from scientists in industry, academia as well as private research institutes, non-governmental and environmental organizations are encouraged.
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