与咪达必利相关的惊厥--罕见病例报告

Shashidhara Kc, Savitha V, Derek Jonathan Edwin, Mirza Asgar Baig, Sai Surya Chukkapalli
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引用次数: 0

摘要

背景:急性杀虫剂中毒是全球关注的健康问题,其中有机磷化合物是主要原因。新烟碱类(如吡虫啉)因其对害虫神经系统的选择性作用而成为替代杀虫剂。本病例报告对吡虫啉中毒进行了探讨,强调了临床表现以及对更安全杀虫剂的不断探索:一名 46 岁的男性,长期吸烟并酗酒,因吡虫啉中毒而自杀。患者出现癫痫发作、中枢神经系统(CNS)抑制、低钠血症和呼吸停止,需要进行机械通气。本病例详细介绍了包括影像学检查在内的综合评估,并介绍了生命体征、实验室结果和体格检查。患者接受了支持性治疗,讨论概述了治疗策略,强调了处理吡虫啉毒性的挑战和成功之处:本病例强调了吡虫啉中毒的复杂性,尤其是注意到了继发于低钠血症的抽搐。报告强调有必要进一步研究吡虫啉的代谢作用,并提倡在此类病例中进行警惕性监测和支持性护理。报告呼吁增加报告次数,以加强对吡虫啉潜在毒性作用的了解和知识共享,从而有助于制定更好的农药中毒管理策略。
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Imidaclopride associated Convulsions - A rare case report
Background: Acute pesticide poisoning is a global health concern, with organophosphorus compounds contributing significantly. Neonicotinoids, like imidacloprid, have emerged as alternative insecticides due to their selective action on pest nervous systems. This case report explores imidacloprid poisoning, emphasizing clinical manifestations and the ongoing search for safer pesticides. Methods: A 46-year-old male, chronic smoker, and alcoholic, presented with suicidal imidacloprid poisoning. The patient experienced seizures, central nervous system (CNS) depression, hyponatremia, and respiratory arrest, necessitating mechanical ventilation. The case details the comprehensive evaluation, including imaging studies, and presents vital signs, laboratory results, and physical examinations. The patient received supportive care, and the discussion outlines the treatment strategy, highlighting the challenges and successes in managing imidacloprid toxicity. Conclusion: This case underscores the complexity of imidacloprid poisoning, particularly noting convulsions secondary to hyponatremia. It stresses the need for further research into imidacloprid's metabolic effects and advocates for vigilant monitoring and supportive care in such cases. The report calls for increased reporting to enhance understanding and knowledge sharing regarding the potential toxic effects of imidacloprid, contributing to better management strategies for pesticide poisoning.
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