在以白人为主的样本中应用并扩展了一种预测注意力缺陷/多动症和障碍的算法。

IF 3.1 Q2 PSYCHIATRY Journal of psychopathology and clinical science Pub Date : 2024-10-01 Epub Date: 2024-08-08 DOI:10.1037/abn0000909
Patrick K Goh, Ashley G Eng, Pevitr S Bansal, Yunjin T Kim, Sarah A Miller, Michelle M Martel, Russell A Barkley
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引用次数: 0

摘要

目前针对注意力缺陷/多动障碍(ADHD)的评估方案主要集中在一系列高度重叠的症状上,而像认知脱离综合征(CDS)、执行功能(EF)、年龄、性别、种族和民族等经过充分验证的因素则通常被忽视。本研究利用机器学习技术,旨在验证最近提出的一组多动症症状子集的研究结果,这些子集共同预测多动症的诊断、严重程度和障碍水平的效果优于完整的症状列表,同时还测试了纳入上述因素是否能进一步提高准确性。1,922 名 6-17 岁儿童(50.1% 为男性)的家长完成了对多动症、多动症综合症、EF 和障碍的评分量表。结果表明,有九种症状对预测结果最为重要:(a) 难以在任务或游戏活动中持续保持注意力;(b) 不听从指令,无法完成作业;(c) 逃避需要完成的任务(如学校作业、家庭作业等);(d) 在学习和生活中缺乏自理能力、(d) 经常容易分心;(e) 难以组织任务和活动;(f) 在日常活动中经常健忘;(g) 坐立不安;(h) 打断/干扰他人;(i) 过度走动或感到不安或局促不安。与包含全部 18 个症状的算法相比,简略算法在预测障碍方面的准确率并无明显差异,同时在预测多动症诊断方面也表现出卓越的鉴别能力。在简略算法中加入 CDS 和 EF 进一步提高了对全面障碍的预测能力。继续改进筛查工具将是确保有多动症风险的青少年获得临床服务的关键。(PsycInfo Database Record (c) 2024 APA,保留所有权利)。
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Application and expansion of an algorithm predicting attention-deficit/hyperactivity disorder and impairment in a predominantly White sample.

Current assessment protocols for attention-deficit/hyperactivity disorder (ADHD) focus heavily on a set of highly overlapping symptoms, with well-validated factors like cognitive disengagement syndrome (CDS), executive function (EF), age, sex, and race and ethnicity generally being ignored. Using machine learning techniques, the current study aimed to validate recent findings proposing a subset of ADHD symptoms that, together, predict ADHD diagnosis, severity, and impairment level better than the full symptom list, while also testing whether the inclusion of the factors listed above could further increase accuracy. Parents of 1,922 children (50.1% male) aged 6-17 years completed rating scales of ADHD, CDS, EF, and impairment. Results suggested nine symptoms as most important in predicting outcomes: (a) has difficulty sustaining attention in tasks or play activities; (b) does not follow through on instructions and fails to finish work; (c) avoids tasks (e.g., schoolwork, homework) that require sustained mental effort; (d) is often easily distracted; (e) has difficulty organizing tasks and activities; (f) is often forgetful in daily activities; (g) fidgets with hands or feet or squirms in seat; (h) interrupts/intrudes on others; and (i) shifts around excessively or feels restless or hemmed in. The abbreviated algorithm achieved accuracy rates that did not significantly differ compared to an algorithm comprising all 18 symptoms in predicting impairment, while also demonstrating excellent discriminative ability in predicting ADHD diagnosis. Adding CDS and EF to the abbreviated algorithm further improved the prediction of global impairment. Continued refinement of screening tools will be key to ensuring access to clinical services for youth at risk for ADHD. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

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