A. Yu. Ershov, A. A. Martynenkov, I. V. Lagoda, A. A. Batyrenko
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Reaction of 5-Hydroxypyrazolidine with Thiol-Containing Hydrazides as a Route to Biologically Active Ligands for Gold Glyconanoparticles
The reaction of (3S)-1-acetyl-5-hydroxy-2-phenyl-3-methylpyrazolidine with 6-mercaptohexanoic and 11-mercaptoundecanoic acid hydrazides gives in 60–65% yields (3S)-1-acetyl-5-[(ω-mercaptoacyl)hydrazino]-2-phenyl-3-methylpyrazolidines, promising coligands for preparing gold glyconanoparticles for the biomedical purpose.
期刊介绍：
Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.
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