韩国人食用含维生素 D 的食物与全因死亡率之间的关系。

IF 1.7 3区 农林科学 Q4 CHEMISTRY, MEDICINAL Journal of medicinal food Pub Date : 2025-01-01 Epub Date: 2024-10-25 DOI:10.1089/jmf.2024.k.0147
Jung Hyun Kwak, Jean Kyung Paik
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引用次数: 0

摘要

据报道,充足的维生素 D 水平是降低各种慢性疾病及其死亡率的一个因素。本研究利用韩国基因组与流行病学研究(KoGES)的数据,证实了死亡率与富含维生素 D 的食物摄入量之间的关联。在KoGES数据库中,我们共跟踪调查了6844名成年人,他们参加了2001年至2002年招募的安城-安山队列研究,平均持续16.7年,直到2018年。主要研究结果采用 Cox 回归分析法进行分析。在随访期间,确认了 439 例全因死亡、149 例癌症相关死亡和 91 例心血管死亡。在完全调整模型中,与四分位数 1 相比,食用蘑菇四分位数 3 的全因死亡率危险比为 0.709(95% 置信区间 [CI],0.525-0.958)。此外,与四分位数 1 相比,食用蘑菇四分位数 3 的心血管死亡率的 HR 值为 0.348(95% 置信区间 [CI],0.154-0.787)。与四分位数 1 相比,鱼类消费量四分位数 3 和 4 的心血管死亡率 HR 分别为 0.442(95% CI,0.226-0.865)和 0.533(95% CI,0.285-0.998)。总之,适量食用蘑菇与全因和心血管死亡风险的降低有关,而大量食用鱼类与心血管死亡成反比。
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Association Between Consumption of Foods Containing Vitamin D and All-Cause Mortality in Korea.

Sufficient vitamin D levels are reported to be a factor in reducing various chronic diseases and resulting mortality rates. Well-dried mushrooms and blue-backed fish are known to be rich in vitamin D. In this study, the association between mortality rates and the intake of vitamin D-rich foods was confirmed using data from the Korean Genome and Epidemiological Study (KoGES). Among the KoGES database, we followed up a total of 6844 adults who participated in the Ansung-Ansan cohort study recruited from 2001 to 2002 and continued for an average of 16.7 years until 2018. The main findings were analyzed using Cox regression analysis. During follow-up, 439 cases of all-cause mortality, 149 cases of cancer-related mortality, and 91 cases of cardiovascular mortality were confirmed. In the fully adjusted model, the hazard ratio (HR) for all-cause mortality in quartile 3 of mushroom consumption was 0.709 (95% confidence interval [CI], 0.525-0.958) compared with quartile 1. In addition, the HRs for cardiovascular mortality in quartile 3 of mushroom consumption were 0.348 (95% CI, 0.154-0.787) compared with those in quartile 1. The HRs of cardiovascular mortality for quartiles 3 and 4 of fish consumption were 0.442 (95% CI, 0.226-0.865) and 0.533 (95% CI, 0.285-0.998), respectively, compared with quartile 1. In conclusion, moderate consumption of mushrooms was related to decreased risk of all-cause and cardiovascular mortality, while heightened fish consumption was inversely related to cardiovascular mortality.

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来源期刊
Journal of medicinal food
Journal of medicinal food 医学-食品科技
CiteScore
4.50
自引率
0.00%
发文量
154
审稿时长
4.5 months
期刊介绍: Journal of Medicinal Food is the only peer-reviewed journal focusing exclusively on the medicinal value and biomedical effects of food materials. International in scope, the Journal advances the knowledge of the development of new food products and dietary supplements targeted at promoting health and the prevention and treatment of disease.
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