Culcinoside E:一种从新海星Culcita novaeguineae中提取的磺化甾体大糖苷。

IF 1.3 3区 医学 Q3 CHEMISTRY, APPLIED Journal of Asian Natural Products Research Pub Date : 2024-12-03 DOI:10.1080/10286020.2024.2434564
Le Thi Vien, Tran Thi Hong Hanh, Tran Hong Quang, Nguyen Dang Ngai, Dao Viet Ha, Nguyen Xuan Cuong
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引用次数: 0

摘要

采用不同的色谱分离方法,从海星Culcita novaeguineae的甲醇提取物中分离到6个甾类苷类衍生物,其中一个新化合物命名为culcinoside E(1)。通过1D, 2D NMR和HR ESI QTOF质谱的详细分析证实了它们的结构。在分离的化合物中,culculsidoside E(1)、diplasterioside A(5)和thornasteroside A(6)抑制粪肠球菌的生长,而culculsidoside C1(3)对白色念珠菌有活性。
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Culcinoside E, a new sulfated steroidal biglycoside from the starfish Culcita novaeguineae.

Using various chromatographic separations, six steroid glycoside derivatives, including one new compound named culcinoside E (1), were isolated from the methanol extract of the starfish Culcita novaeguineae. Their structures were confirmed by detailed analysis of the 1D, 2D NMR, and HR ESI QTOF mass spectra. Among isolated compounds, culcinoside E (1), diplasterioside A (5), and thornasteroside A (6) inhibited growth of Enterococcus faecalis, whereas culcitoside C1 (3) was active on Candida albicans.

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来源期刊
CiteScore
3.20
自引率
5.90%
发文量
47
审稿时长
2.3 months
期刊介绍: The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.
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