评估人体暴露于鱼类中的有机污染物:一种整合化学生物浓缩和食品热加工的建模方法。

Q1 Environmental Science Toxicology Reports Pub Date : 2024-11-13 eCollection Date: 2024-12-01 DOI:10.1016/j.toxrep.2024.101805
Jie Xiong, Yuan Zhang, Zijian Li
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引用次数: 0

摘要

在环境中发现的越来越多的化学物质可能对鱼类等生物构成威胁。风险评估模型是至关重要的资源,能够测量与化学品接触有关的危害。然而,传统的监测技术和实验程序无法跟上与环境问题牵连越来越多的化合物的步伐。此外,大量的数据必然导致不准确。在这里,我们提出了一种结合机器学习和模糊逻辑数学方法的综合方法,以尽可能少的数据输入评估与受污染鱼类的化学暴露相关的风险。我们预测了环境中有机污染物的浓度,作为量化家庭鱼类热加工过程中模糊风险的基线。水环境中化学物质浓度是预测生物浓度因子的最重要因素,平均r2值为0.78。与其他农药相比,七氯、内砜硫酸盐、Endrin和Endrin醛是整个加工过程中高风险的四种农药。研究结果强调了考虑加工方法和环境因素以确保食品安全的重要性。
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Assessing human exposure to organic contaminants in fish: A modeling approach integrating chemical bioconcentration and food thermal processing.

An increasing number of chemicals found in the environment potentially pose a threat to organisms such as fish. Models for risk assessment are vital resources that enable possible measurements of the hazards associated with chemical exposure. Traditional monitoring techniques and experimental procedures, however, are unable to keep up with the compounds that are becoming more and more implicated in environmental problems. Furthermore, a significant amount of data invariably results in inaccuracies. Here, we proposed an integrated approach that combines machine learning and fuzzy logic mathematical methods, assessing the risks associated with chemical exposure from contaminated fish with the least amount of data entry possible. We predicted the concentrations of organic contaminants in the environment, serving as a baseline for quantifying the fuzzy risks during household thermal processing of the fish. With a mean R 2 value of 0.78, concentration of chemicals in the aquatic environment emerged as the most influential factor in predicting bioconcentration factors. Heptachlor, Endosulfan-sulfate, Endrin, and Endrin aldehyde are four high-risk pesticides throughout the entire processing process compared to others. The findings underscore the importance of considering processing methods and environmental factors in order to ensure food safety.

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来源期刊
Toxicology Reports
Toxicology Reports Environmental Science-Health, Toxicology and Mutagenesis
CiteScore
7.60
自引率
0.00%
发文量
228
审稿时长
11 weeks
期刊最新文献
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