{"title":"新生儿性别对哺乳期早期母乳中微量元素含量的影响","authors":"Banin Shakeri Jooybari, Fatemeh Nasri Nasrabadi, Abdoulreza Esteghamati","doi":"10.1089/bfm.2024.0226","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Objectives:</i></b> This study aimed to investigate the influence of newborns' sex on the concentrations of minor and trace elements in the human milk of lactating mothers during early lactation. The elemental analysis focused on calcium (Ca), potassium (K), sodium (Na), and chlorine (Cl) as minor elements and iodine (I), aluminum (Al), bromine (Br), and rubidium (Rb) as trace elements. <b><i>Methods:</i></b> Breast milk samples were collected from 75 lactating mothers in Tehran, Iran, during the early feeding stage. Neutron activation analysis was used to quantify elemental amounts in milk samples, and <i>t</i> tests were conducted to identify statistical differences in element levels between mothers of male and female newborns. <b><i>Results:</i></b> Statistically significant differences in the elemental composition of milk samples were found based on newborn infants' sex. Mothers of female newborns had notably higher mean levels of Br (14.8 mg/kg versus 11.3 mg/kg, <i>p</i> = 0.011), Cl (10.16 mg/g versus 7.10 mg/g, <i>p</i> = 0.009), and Na (6.18 mg/g versus 4.45 mg/g, <i>p</i> = 0.017) compared with mothers with male newborns. Although Ca, K, I, Al, and Rb did not show statistically substantial differences, there was a trend toward elevated levels of Al, I, and Ca in the milk of mothers with the females. <b><i>Conclusion:</i></b> The analysis reveals sex-based variations in human milk composition, with elevated levels of Br, Cl, and Na observed in mothers of female newborns. These findings suggest that infant sex may influence the elemental profile of maternal milk, highlighting the need for further research to uncover the mechanisms behind these differences and their potential implications for improving infant nutrition and health.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Influence of Newborns' Sex on Minor and Trace Element Concentrations in Human Milk During Early Lactation.\",\"authors\":\"Banin Shakeri Jooybari, Fatemeh Nasri Nasrabadi, Abdoulreza Esteghamati\",\"doi\":\"10.1089/bfm.2024.0226\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b><i>Objectives:</i></b> This study aimed to investigate the influence of newborns' sex on the concentrations of minor and trace elements in the human milk of lactating mothers during early lactation. The elemental analysis focused on calcium (Ca), potassium (K), sodium (Na), and chlorine (Cl) as minor elements and iodine (I), aluminum (Al), bromine (Br), and rubidium (Rb) as trace elements. <b><i>Methods:</i></b> Breast milk samples were collected from 75 lactating mothers in Tehran, Iran, during the early feeding stage. Neutron activation analysis was used to quantify elemental amounts in milk samples, and <i>t</i> tests were conducted to identify statistical differences in element levels between mothers of male and female newborns. <b><i>Results:</i></b> Statistically significant differences in the elemental composition of milk samples were found based on newborn infants' sex. Mothers of female newborns had notably higher mean levels of Br (14.8 mg/kg versus 11.3 mg/kg, <i>p</i> = 0.011), Cl (10.16 mg/g versus 7.10 mg/g, <i>p</i> = 0.009), and Na (6.18 mg/g versus 4.45 mg/g, <i>p</i> = 0.017) compared with mothers with male newborns. Although Ca, K, I, Al, and Rb did not show statistically substantial differences, there was a trend toward elevated levels of Al, I, and Ca in the milk of mothers with the females. <b><i>Conclusion:</i></b> The analysis reveals sex-based variations in human milk composition, with elevated levels of Br, Cl, and Na observed in mothers of female newborns. These findings suggest that infant sex may influence the elemental profile of maternal milk, highlighting the need for further research to uncover the mechanisms behind these differences and their potential implications for improving infant nutrition and health.</p>\",\"PeriodicalId\":9142,\"journal\":{\"name\":\"Breastfeeding Medicine\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-12-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Breastfeeding Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1089/bfm.2024.0226\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Breastfeeding Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/bfm.2024.0226","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
目的:探讨新生儿性别对哺乳期母亲母乳中微量元素含量的影响。元素分析的重点是钙(Ca)、钾(K)、钠(Na)和氯(Cl)作为微量元素,碘(I)、铝(Al)、溴(Br)和铷(Rb)作为微量元素。方法:采集伊朗德黑兰75名哺乳期母亲早期喂养期的母乳样本。使用中子活化分析来量化牛奶样品中的元素含量,并进行t检验来确定男性和女性新生儿母亲之间元素水平的统计差异。结果:根据新生儿的性别,牛奶样品的元素组成有统计学上的显著差异。女性新生儿母亲的平均Br (14.8 mg/kg对11.3 mg/kg, p = 0.011)、Cl (10.16 mg/g对7.10 mg/g, p = 0.009)和Na (6.18 mg/g对4.45 mg/g, p = 0.017)水平明显高于男性新生儿母亲。虽然Ca、K、I、Al和Rb在统计学上没有显著差异,但母鼠的乳汁中Al、I和Ca的含量有升高的趋势。结论:该分析揭示了母乳成分的性别差异,在女性新生儿的母亲中观察到Br、Cl和Na水平升高。这些发现表明,婴儿性别可能会影响母乳的元素特征,强调需要进一步研究揭示这些差异背后的机制及其对改善婴儿营养和健康的潜在影响。
Influence of Newborns' Sex on Minor and Trace Element Concentrations in Human Milk During Early Lactation.
Objectives: This study aimed to investigate the influence of newborns' sex on the concentrations of minor and trace elements in the human milk of lactating mothers during early lactation. The elemental analysis focused on calcium (Ca), potassium (K), sodium (Na), and chlorine (Cl) as minor elements and iodine (I), aluminum (Al), bromine (Br), and rubidium (Rb) as trace elements. Methods: Breast milk samples were collected from 75 lactating mothers in Tehran, Iran, during the early feeding stage. Neutron activation analysis was used to quantify elemental amounts in milk samples, and t tests were conducted to identify statistical differences in element levels between mothers of male and female newborns. Results: Statistically significant differences in the elemental composition of milk samples were found based on newborn infants' sex. Mothers of female newborns had notably higher mean levels of Br (14.8 mg/kg versus 11.3 mg/kg, p = 0.011), Cl (10.16 mg/g versus 7.10 mg/g, p = 0.009), and Na (6.18 mg/g versus 4.45 mg/g, p = 0.017) compared with mothers with male newborns. Although Ca, K, I, Al, and Rb did not show statistically substantial differences, there was a trend toward elevated levels of Al, I, and Ca in the milk of mothers with the females. Conclusion: The analysis reveals sex-based variations in human milk composition, with elevated levels of Br, Cl, and Na observed in mothers of female newborns. These findings suggest that infant sex may influence the elemental profile of maternal milk, highlighting the need for further research to uncover the mechanisms behind these differences and their potential implications for improving infant nutrition and health.
期刊介绍:
Breastfeeding Medicine provides unparalleled peer-reviewed research, protocols, and clinical applications to ensure optimal care for mother and infant. The Journal answers the growing demand for evidence-based research and explores the immediate and long-term outcomes of breastfeeding, including its epidemiologic, physiologic, and psychological benefits. It is the exclusive source of the Academy of Breastfeeding Medicine protocols.
Breastfeeding Medicine coverage includes:
Breastfeeding recommendations and protocols
Health consequences of artificial feeding
Physiology of lactation and biochemistry of breast milk
Optimal nutrition for the breastfeeding mother
Breastfeeding indications and contraindications
Managing breastfeeding discomfort, pain, and other complications
Breastfeeding the premature or sick infant
Breastfeeding in the chronically ill mother
Management of the breastfeeding mother on medication
Infectious disease transmission through breast milk and breastfeeding
The collection and storage of human milk and human milk banking
Measuring the impact of being a “baby-friendly” hospital
Cultural competence and cultural sensitivity
International public health issues including social and economic issues.