S Govoni, G Pasinetti, A Bianchi, M Gadola, M Trabucchi
{"title":"大量饮酒可降低血浆脑啡肽浓度。","authors":"S Govoni, G Pasinetti, A Bianchi, M Gadola, M Trabucchi","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Plasma met-enkephalin immunoreactive material (ME-IR) concentration was measured in 175 aged subjects (68 males, 107 females). Heavy drinking (1 liter of red or white wine a day, equivalent roughly to greater than 110 g ethanol) was associated with reduced ME-IR concentrations. On the other hand, no correlation was found between plasma ME-IR and other parameters such as blood pressure, age or body weight. These data favor the hypothesis of an involvement of ME-IR in the mechanisms of ethanol action.</p>","PeriodicalId":7671,"journal":{"name":"Alcohol and drug research","volume":"7 2","pages":"93-8"},"PeriodicalIF":0.0000,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Heavy drinking decreases plasma met-enkephalin concentrations.\",\"authors\":\"S Govoni, G Pasinetti, A Bianchi, M Gadola, M Trabucchi\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Plasma met-enkephalin immunoreactive material (ME-IR) concentration was measured in 175 aged subjects (68 males, 107 females). Heavy drinking (1 liter of red or white wine a day, equivalent roughly to greater than 110 g ethanol) was associated with reduced ME-IR concentrations. On the other hand, no correlation was found between plasma ME-IR and other parameters such as blood pressure, age or body weight. These data favor the hypothesis of an involvement of ME-IR in the mechanisms of ethanol action.</p>\",\"PeriodicalId\":7671,\"journal\":{\"name\":\"Alcohol and drug research\",\"volume\":\"7 2\",\"pages\":\"93-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1987-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Alcohol and drug research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alcohol and drug research","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Heavy drinking decreases plasma met-enkephalin concentrations.
Plasma met-enkephalin immunoreactive material (ME-IR) concentration was measured in 175 aged subjects (68 males, 107 females). Heavy drinking (1 liter of red or white wine a day, equivalent roughly to greater than 110 g ethanol) was associated with reduced ME-IR concentrations. On the other hand, no correlation was found between plasma ME-IR and other parameters such as blood pressure, age or body weight. These data favor the hypothesis of an involvement of ME-IR in the mechanisms of ethanol action.
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