[Problem solving of the clinical case-method type for the development of clinical thinking. The illustrative problem of galactosemia].

Problem-solving case approach is an effective method for teaching clinical concepts. This method makes medical students be aware of the significance of Biochemistry for the clinical practice. The students are stimulated to study basic biochemical principles. The complete text of a problem case on galactosemia is presented. This case, usually given to the students during the final seminar on carbohydrate metabolism reflects a real situation, in which the student feels responsible to make decisions. He has to make the diagnosis and prescribe a treatment. The student's actions are assessed and commented. The students took a great interest in that problem case and that shows that it is possible and necessary even in the second preclinical year to joint the theoretical principles with the future clinical practice.