拉丁美洲和加勒比地区水中抗菌素耐药性:范围审查议定书。

Andrea I Moreno-Switt, Dacil Rivera, Marisa L Caipo, David C Nowell, Aiko D Adell
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引用次数: 0

摘要

目的:本次范围界定审查的目的是确定和绘制拉丁美洲和加勒比(LAC)水中抗菌药物耐药性(AMR)的现有证据,同时确定该地区在八个感兴趣的主题中的抗菌药物耐药性信息差距。引言:抗微生物耐药性是一个日益引起全球关注的公共卫生问题。人们对环境在临床相关AMR传播中的作用的重要性表示担忧。尽管已经对AMR进行了研究,但尚未对拉丁美洲和加勒比地区环境作用的现实情况进行研究。纳入标准:研究拉丁美洲和加勒比地区水中AMR的文章将被考虑纳入。抗微生物耐药性将被定义为一种自然过程,当引起感染的微生物(如细菌)暴露在通常会杀死它们或阻止它们生长的药物中后存活下来。搜索将集中在协议中定义的八个感兴趣的主题上,这些主题与水源中存在耐药性微生物和报告的负面健康影响有关。将考虑纳入定性和定量研究。评论和灰色文献将被排除在外。方法:拟议的范围审查将根据JBI范围审查方法进行。将在PubMed、Web of Science和Scopus上搜索已发表的文献。文章的独立筛选将通过审查摘要和全文,利用预先定义的纳入和排除标准进行。将提取特定变量的数据,并进行描述性检查。
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Antimicrobial resistance in water in Latin America and the Caribbean: a scoping review protocol.

Objective: The objective of this scoping review is to identify and map existing evidence of antimicrobial resistance (AMR) in water in Latin America and the Caribbean (LAC), while also identifying the gaps in AMR information in the region in eight themes of interest.

Introduction: Antimicrobial resistance is a public health concern that has gained increasing global awareness. Concerns have been raised toward the importance of the environment's role in the dissemination of clinically relevant AMR. Although studies on AMR have been conducted, the reality of the role of the environment in the LAC region has not been studied.

Inclusion criteria: Articles that examine AMR in water in the LAC region will be considered for inclusion. Antimicrobial resistance will be defined as a natural process that arises when the microorganisms that cause infection (e.g. bacteria) survive exposure to a drug that would normally kill them or stop their growth. The search will focus on eight themes of interest, as defined in the protocol, relating to the presence of resistant microorganisms in water sources and reported negative health effects. Qualitative and quantitative studies will be considered for inclusion. Reviews and gray literature will be excluded.

Methods: The proposed scoping review will be conducted in accordance with the JBI methodology for scoping reviews. A search for published literature will be performed in PubMed, Web of Science and Scopus. Independent screening of articles will be performed by examining the abstracts and then the full texts, utilizing pre-defined inclusion and exclusion criteria. Data for specific variables will be extracted, and descriptive examination will be performed.

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