基于嗅探棒试验的重复测量设计中嗅觉阈值快速有效评估新方法

IF 1 4区 医学 Q4 Neuroscience Chemosensory Perception Pub Date : 2021-10-01 DOI:10.1007/s12078-021-09291-6
Sarah Beutler, Liliana R. Ladner, Thomas Hummel, Ilona Croy
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引用次数: 0

摘要

嗅探棒阈值测试因其高信度和效度而被广泛应用于嗅觉阈值评估。然而,这个测试过程相当长,平均持续时间为10到20分钟。在需要在短时间间隔内进行多次嗅觉阈值测试的研究设计中,这可能会使参与者筋疲力尽。为了克服这一限制,我们开发了重复测量设计的嗅探棒阈值测试的通知四反转(INFOUR)简短版本,并在正常参与者的样本中进行了试验。方法42名参与者在被分配到重复原始版本的对照组和执行INFOUR简短版本的试验组之前,先执行原始版本的嗅探棒。结果T1时的原始版本与T2时的INFOUR相关r =。75且与原始版本的重测信度无显著差异。与原始版本相比,INFOUR的执行时间减少了42%。结论INFOUR在节省时间的同时保持了良好的有效性。因此,这种方法有可能成为具有重复嗅觉阈值测量的研究方案的有用工具。特别是,当研究方案时间密集或测试需要缩短时,因为干预效果是短暂或微妙的。
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A New Method for a Shorter and Valid Assessment of Olfactory Threshold in Repeated Measurement Designs Based on the Sniffin’ Sticks Test

Introduction

The Sniffin’ Sticks threshold test is widely used to assess olfactory threshold due to its high reliability and validity. Nevertheless, this test procedure is quite long with an average duration of 10 to 20 min. In study designs that require multiple olfactory threshold tests on short intervals, this could exhaust participants. To counteract this limitation, we developed the informed-four-reversal (INFOUR) short version of the Sniffin’ Sticks threshold test for repeated measurement designs and piloted it in a sample of normosmic participants.

Methods

Forty-two participants performed the original Sniffin’ Sticks version before being assigned either to the control group that repeated the original version or to the test group that conducted the INFOUR short version.

Results

The correlation between the original version at T1 and INFOUR at T2 was r = .75 and did not differ significantly from the retest reliability of the original version. Compared to the original version, the INFOUR took 42% less time to perform.

Conclusion

The INFOUR leads to a significant time saving, while maintaining good validity.

Implications

Therefore, this approach has the potential to be a useful tool for study protocols with repeated olfactory threshold measurements. In particular, when research protocols are time intensive or testing needs to the shortened, because the interventional effects are short or subtle.

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来源期刊
Chemosensory Perception
Chemosensory Perception 农林科学-神经科学
CiteScore
2.50
自引率
0.00%
发文量
8
审稿时长
>36 weeks
期刊介绍: Coverage in Chemosensory Perception includes animal work with implications for human phenomena and explores the following areas: Identification of chemicals producing sensory response; Identification of sensory response associated with chemicals; Human in vivo response to chemical stimuli; Human in vitro response to chemical stimuli; Neuroimaging of chemosensory function; Neurological processing of chemoreception; Chemoreception mechanisms; Psychophysics of chemoperception; Trigeminal function; Multisensory perception; Contextual effect on chemoperception; Behavioral response to chemical stimuli; Physiological factors affecting and contributing to chemoperception; Flavor and hedonics; Memory and chemoperception.
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