炎症性肠病发病机制中的锌水平

Pub Date : 2021-10-01 DOI:10.1097/TIN.0000000000000261
Mingqian Zhang, Zong-bi Yi, Liyan Ma, Shaoshuo Li, Long Han, Qi Cao
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引用次数: 1

摘要

本研究旨在通过荟萃分析研究血清锌水平(SZL)与炎症性肠病(IBD)风险之间的关系。从不同的数据库中检索到在IBD患者和健康对照中报告SZL的人体研究。在123篇已确定的文章中,只有16篇符合我们的标准,并进行了数据提取和分析。我们的分析表明SZL与克罗恩病之间存在显著关系。SZL与溃疡性结肠炎无明显相关性。总之,荟萃分析的结果表明,低SZL与克罗恩病风险之间存在显著关联,但与溃疡性结肠炎无关。
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Zinc Level in Pathogenesis of Inflammatory Bowel Disease
This study aimed to investigate the relationship between serum zinc levels (SZL) and inflammatory bowel disease (IBD) risk via a meta-analysis. Human studies that have reported SZL in patients with IBD and healthy controls were retrieved from different databases. Of the 123 identified articles, only 16 met our criteria and were examined for data extraction and analysis. Our analysis demonstrated a significant relationship between SZL and Crohn's disease. There was no significant relationship between SZL and ulcerative colitis. In conclusion, the results of the meta-analysis indicate a significant association between low SZL and the risk of Crohn's disease, but not ulcerative colitis.
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