Hartatiek, M. I. Wuriantika, S. Amalia, Masruroh, Yudyanto, M. Nurhuda, D. Santjojo
{"title":"PVA/壳聚糖/PEG/HAp纳米纤维支架的等离子体表面改性及其形态、润湿性和生物降解率的研究","authors":"Hartatiek, M. I. Wuriantika, S. Amalia, Masruroh, Yudyanto, M. Nurhuda, D. Santjojo","doi":"10.1088/2043-6262/accc7b","DOIUrl":null,"url":null,"abstract":"Nanofiber scaffold has been widely developed as a tissue engineering material because it can imitate the ECM of bones. In this study, nanofiber scaffold is composed of polyvinyl alcohol (PVA), chitosan, polyethylene glycol (PEG), and hydroxyapatite (HAp) which have superior characteristics for tissue engineering applications. The nanofiber scaffold is synthesized using electrospinning. Experimental results show that dielectric barrier discharge (DBD) plasma treatment causes increased surface roughness, contributing to the improvement of surface wettability. This is indicated by a decrease in this contact angle from 9.92° to 1.74°. In addition, DBD plasma treatment also increased biodegradation as well as increased treatment time.","PeriodicalId":7359,"journal":{"name":"Advances in Natural Sciences: Nanoscience and Nanotechnology","volume":" ","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Surface modification of PVA/Chitosan/PEG/HAp nanofiber scaffolds by plasma treatment and studies of their morphology, wettability, and biodegradation rate\",\"authors\":\"Hartatiek, M. I. Wuriantika, S. Amalia, Masruroh, Yudyanto, M. Nurhuda, D. Santjojo\",\"doi\":\"10.1088/2043-6262/accc7b\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Nanofiber scaffold has been widely developed as a tissue engineering material because it can imitate the ECM of bones. In this study, nanofiber scaffold is composed of polyvinyl alcohol (PVA), chitosan, polyethylene glycol (PEG), and hydroxyapatite (HAp) which have superior characteristics for tissue engineering applications. The nanofiber scaffold is synthesized using electrospinning. Experimental results show that dielectric barrier discharge (DBD) plasma treatment causes increased surface roughness, contributing to the improvement of surface wettability. This is indicated by a decrease in this contact angle from 9.92° to 1.74°. In addition, DBD plasma treatment also increased biodegradation as well as increased treatment time.\",\"PeriodicalId\":7359,\"journal\":{\"name\":\"Advances in Natural Sciences: Nanoscience and Nanotechnology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2023-05-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Natural Sciences: Nanoscience and Nanotechnology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1088/2043-6262/accc7b\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Natural Sciences: Nanoscience and Nanotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1088/2043-6262/accc7b","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Surface modification of PVA/Chitosan/PEG/HAp nanofiber scaffolds by plasma treatment and studies of their morphology, wettability, and biodegradation rate
Nanofiber scaffold has been widely developed as a tissue engineering material because it can imitate the ECM of bones. In this study, nanofiber scaffold is composed of polyvinyl alcohol (PVA), chitosan, polyethylene glycol (PEG), and hydroxyapatite (HAp) which have superior characteristics for tissue engineering applications. The nanofiber scaffold is synthesized using electrospinning. Experimental results show that dielectric barrier discharge (DBD) plasma treatment causes increased surface roughness, contributing to the improvement of surface wettability. This is indicated by a decrease in this contact angle from 9.92° to 1.74°. In addition, DBD plasma treatment also increased biodegradation as well as increased treatment time.
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